ArticleAntimicrobial agents and chemotherapy2013
Rectal swabs are suitable for quantifying the carriage load of KPC-producing carbapenem-resistant Enterobacteriaceae.
Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07685132 (Correlation Between Carbapenemase-Producing Enterobacterales Load, Environmental Contamination, and Transmission in Critical Care Units), which is not on this map. Cited by 26 papers.
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Correlation Between Carbapenemase-Producing Enterobacterales Load, Environmental Contamination, and Transmission in Critical Care Units
Who cites it
26 citing papers in PubMed.
- Risk factors associated with rectal carriage of carbapenem resistant Enterobacterales in northern Nigeria: a hospital surveillance.BMC infectious diseases · 2025Article
- Antibiotic resistance pattern of multidrug-resistant Enterobacterales from a rectal surveillance study in northern Nigeria.International health · 2025Article
- Phage-Mediated Digestive Decolonization in a Gut-On-A-Chip Model: A Tale of Gut-Specific Bacterial Prosperity.Viruses · 2024Article
- The molecular detection of carbapenem markers with a two-levels amplification screening protocol: epidemiological and resistome insights.Frontiers in microbiology · 2024Article
- High frequency of carbapenem-resistant Enterobacteriaceae fecal carriage among ICU hospitalized patients from Southern Iran.Iranian journal of basic medical sciences · 2022Article
- Prognostic Significance of the Relative Load of KPC-Producing Klebsiella pneumoniae within the Intestinal Microbiota in a Prospective Cohort of Colonized Patients.Microbiology spectrum · 2022Observational
- Mortality in Thai Nursing Homes Based on Antimicrobial-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- The Gastrointestinal Load of Carbapenem-Resistant Enterobacteriacea Is Associated With the Transition From Colonization to Infection byFrontiers in cellular and infection microbiology · 2022Article
- Comparison of stool samples and rectal swabs with and without pre-enrichment for the detection of third-generation cephalosporin-resistant Enterobacterales (3GCREB).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Quantitative analysis and virulence phenotypes of atypical enteropathogenicGut microbes · 2020Article
- Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.Intensive care medicine · 2020Article
- Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistance.eLife · 2020Observational
- A prospective study in severely injured patients reveals an altered gut microbiome is associated with transfusion volume.The journal of trauma and acute care surgery · 2019Observational
- Molecular Epidemiology and Risk Factors of Ventilator-Associated Pneumonia Infection Caused by Carbapenem-Resistant Enterobacteriaceae.Frontiers in pharmacology · 2019Article
- Amplification of Antimicrobial Resistance in Gut Flora of Patients Treated with Ceftriaxone.Antimicrobial agents and chemotherapy · 2017Observational
- Infection prevention and control measures and tools for the prevention of entry of carbapenem-resistantAntimicrobial resistance and infection control · 2017Article
- Evaluation of the Swabbing of Disposable Absorbent Incontinence Products for Assessing the Carriage of Multiresistant Enterobacteriaceae in Nursing Home Residents.Frontiers in microbiology · 2017Article
- Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.Clinical microbiology reviews · 2016Review
- Article
- The pros, cons, and unknowns of search and destroy for carbapenem-resistant enterobacteriaceae.Current infectious disease reports · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is more convenient and practical to collect rectal swabs than stool specimens to study carriage of colon pathogens. In this study, we examined the ability to use rectal swabs rather than stool specimens to quantify Klebsiella pneumoniae carbapenemase (KPC)-producing carbapenem-resistant Enterobacteriaceae (CRE). We used a quantitative real-time PCR (qPCR) assay to determine the concentration of the bla(KPC) gene relative to the concentration of 16S rRNA genes and a quantitative culture-based method to quantify CRE relative to total aerobic bacteria. Our results demonstrated that rectal swabs are suitable for quantifying the concentration of KPC-producing CRE and that qPCR showed higher correlation between rectal swabs and stool specimens than the culture-based method.
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