Evidence map›Paper›PMID 23295869›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2012

Malignancies in HIV/AIDS patients attending an outpatient clinic in Vitória, State of Espírito Santo, Brazil.

Lauro Ferreira da Silva Pinto Neto, Maria da Conceição Milanez, Jonathan Eric Golub, Angelica Espinosa Barbosa Miranda

Abstract read
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Incidence and risk of lung cancer in HIV-infected patients.Journal of cancer research and clinical oncology · 2013
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lauro Ferreira da Silva Pinto NetoDepartamento de Clínica Médica, Escola Superior de Ciências, Vitória, ES. lauro.neto@emescam.br
Maria da Conceição Milanez
Jonathan Eric Golub
Angelica Espinosa Barbosa Miranda

Funding

Innovative Approaches for Tuberculosis Control in BrazilU2RTW006885 · FIC · JOHNS HOPKINS UNIVERSITY · PI GOLUB, JONATHAN E. · 2005 to 2014
$2.3M
Epidemiologic Strategies for Tuberculosis ControlK01AI066994 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GOLUB, JONATHAN E. · 2005 to 2009
$564k
FIC NIH HHS U2R TW006885NIAID NIH HHS AI066994NIAID NIH HHS K01 AI066994PHS HHS U2RTW006885
6 · The paper itself

Abstract

introductionThe present study investigated cancer prevalence and associated factors among HIV-infected individuals attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil.

methodsA sectional study was conducted among HIV infected adults attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil. Demographic, epidemiological and clinical data were abstracted from medical records, including cancer diagnoses; nadir and current CD4 cell count, HIV viral load, time on antiretroviral treatment (ART), type of ART and smoking status.

resultsA total of 730 (91.3%) patients were included in the study. Median age was 44.0 [interquartile range (IQR): 35-50.3] years; median time since HIV diagnosis was 5.5 years (IQR: 2-10); 60% were male; and 59% were white. Thirty (4.1%) cases of cancer were identified of which 16 (53%) were AIDS defining cancers and 14 (47%) were non-AIDS defining malignancies. Patients diagnosed with cancer presented higher chance of being tobacco users [OR 2.2 (95% CI: 1.04-6.24)]; having nadir CD4 ≤200 cells/mm³ [OR 3.0 (95% CI: 1.19-7.81)] and higher lethality [OR 13,3 (95% CI: 4,57-38,72)].

conclusionsThese results corroborate the importance of screening for and prevention of non-AIDS defining cancers focus in HIV-infected population, as these cancers presented with similar frequency as AIDS defining cancers.

Indexed as

AdultAnti-HIV AgentsBrazilCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedNeoplasmsPrevalenceRisk FactorsViral LoadAnti-HIV Agents

Identifiers

PMID23295869
PMCPMC6278945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.