Evidence map›Paper›PMID 23295603›Full record

ArticleClinics (Sao Paulo, Brazil)2012

The effects of exercise modalities on adiposity in obese rats.

Guilherme Fleury Fina Speretta, Marisa Cristina Rosante, Fernanda Oliveira Duarte, Richard Diego Leite, Anderson Diogo de Souza Lino, Rafael Arquias Andre, João Guilherme de Oliveira Silvestre, Heloisa Sobreiro Selistre de Araujo, Ana Claudia Garcia de Oliveira Duarte

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 79 citations in OpenAlex.

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  14. Importance of AT1 and AT2 receptors in the nucleus of the solitary tract in cardiovascular responses induced by a high-fat diet.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Guilherme Fleury Fina SperettaFederal University of São Carlos, Department of Physical Education, Center of Biological and Health Sciences, Laboratory of Nutrition and Metabolism Applied to Exercise, São Carlos/SP, Brazil. gsperetta@gmail.com
Marisa Cristina Rosante
Fernanda Oliveira Duarte
Richard Diego Leite
Anderson Diogo de Souza Lino
Rafael Arquias Andre
João Guilherme de Oliveira Silvestre
Heloisa Sobreiro Selistre de Araujo
Ana Claudia Garcia de Oliveira Duarte
Universidade Federal de São Carlos · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to evaluate the effect of both swimming and resistance training on tumor necrosis factor-alpha and interleukin-10 expression, adipocyte area and lipid profiles in rats fed a high-fat diet.

methodsThe study was conducted over an eight-week period on Wistar adult rats, who were divided into six groups as follows (n = 10 per group): sedentary chow diet, sedentary high-fat diet, swimming plus chow diet, swimming plus high-fat diet, resistance training plus chow diet, and resistance training plus high-fat diet. Rats in the resistance training groups climbed a vertical ladder with weights on their tails once every three days. The swimming groups swam for 60 minutes/day, five days/week.

resultsThe high-fat diet groups had higher body weights, a greater amount of adipose tissue, and higher tumor necrosis factor-alpha expression in the visceral adipose tissue. Furthermore, the high-fat diet promoted a negative change in the lipid profile. In the resistance training high-fat group, the tumor necrosis factor-alpha expression was lower than that in the swimming high-fat and sedentary high-fat groups. Moreover, smaller visceral and retroperitoneal adipocyte areas were found in the resistance training high-fat group than in the sedentary high-fat group. In the swimming high-fat group, the tumor necrosis factor-alpha expression was lower and the epididymal and retroperitoneal adipocyte areas were smaller compared with the sedentary high-fat group.

conclusionThe results showed that both exercise modalities improved the lipid profile, adiposity and obesity-associated inflammation in rats, suggesting their use as an alternative to control the deleterious effects of a high-fat diet in humans.

Indexed as

Diet, High-FatLipid MetabolismPhysical Conditioning, AnimalAdiposityAnalysis of VarianceAnimalsInterleukin-10MaleModels, AnimalRandom AllocationRatsRats, WistarSwimmingTumor Necrosis Factor-alphaInterleukin-10Tumor Necrosis Factor-alpha

Identifiers

PMID23295603
PMCPMC3521812
OpenAlexW2006385173

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.