Evidence map›Paper›PMID 23295590›Full record

ArticleClinics (Sao Paulo, Brazil)2012

Mechanical thrombectomy with solitaire stent retrieval for acute ischemic stroke in a Brazilian population.

Luis Henrique de Castro-Afonso, Thiago Giansante Abud, Octávio Marques Pontes-Neto, Lucas Moretti Monsignore, Guilherme Seizem Nakiri, Pedro Telles Cougo-Pinto, Lívia de Oliveira, Daniela dos Santos, Francisco A Dias, Soraia Cabette Ramos Fábio and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Luis Henrique de Castro-AfonsoUniversity of São Paulo, Medical School of Ribeirão Preto, Division of Interventional Neuroradiology, Ribeirão Preto/SP, Brazil.
Thiago Giansante Abud
Octávio Marques Pontes-Neto
Lucas Moretti Monsignore
Guilherme Seizem Nakiri
Pedro Telles Cougo-Pinto
Lívia de Oliveira
Daniela dos Santos
Francisco A Dias
Soraia Cabette Ramos Fábio
Francisco Antônio Coletto
Daniel Giansante Abud
Universidade de Ribeirão Preto · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLarge vessel occlusion in acute ischemic stroke is associated with low recanalization rates under intravenous thrombolysis. We evaluated the safety and efficacy of the Solitaire AB stent in treating acute ischemic stroke.

methodsPatients presenting with acute ischemic stroke were prospectively evaluated. The neurological outcomes were assessed using the National Institutes of Health Stroke Scale and the modified Rankin Scale. Time was recorded from the symptom onset to the recanalization and procedure time. Recanalization was assessed using the thrombolysis in cerebral infarction score.

resultsTwenty-one patients were evaluated. The mean patient age was 65, and the National Institutes of Health Stroke Scale scores ranged from 7 to 28 (average 17 ± 6.36) at presentation. The vessel occlusions occurred in the middle cerebral artery (61.9%), distal internal carotid artery (14.3%), tandem carotid occlusion (14.3%), and basilarartery (9.5%). Primary thrombectomy, rescue treatment and a bridging approach represented 66.6%, 28.6%, and 4.8% of the performed procedures, respectively. The mean time from symptom onset to recanalization was 356.5 ± 107.8 minutes (range, 80-586 minutes). The mean procedure time was 60.4 ± 58.8 minutes (range, 14-240 minutes). The overall recanalization rate (thrombolysis in cerebral infarction scores of 3 or 2b) was 90.4%, and the symptomatic intracranial hemorrhage rate was 14.2%. The National Institutes of Health Stroke Scale scores at discharge ranged from 0 to 25 (average 6.9 ± 7). At three months, 61.9% of the patients had a modified Rankin Scale score of 0 to 2, with an overall mortality rate of 9.5%.

conclusionsIntra-arterial thrombectomy with the Solitaire AB device appears to be safe and effective. Large randomized trials are necessary to confirm the benefits of this approach in acute ischemic stroke.

Indexed as

StentsAgedBrazilDevice RemovalFemaleFollow-Up StudiesHumansMaleMechanical ThrombolysisProspective StudiesStrokeTreatment OutcomeUltrasonography

Identifiers

PMID23295590
PMCPMC3521799
OpenAlexW2135674715

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.