Evidence map›Paper›PMID 23293947›Full record

ArticleOrganic letters2013

Fluorous supported modular synthesis of heparan sulfate oligosaccharides.

Chengli Zong, Andre Venot, Omkar Dhamale, Geert-Jan Boons

Abstract read
In one paragraph

Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Fluorous-Tag-Assisted Synthesis of GAG-Like Oligosaccharides.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  7. Review
  8. Glycans in drug discovery.MedChemComm · 2019
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chengli ZongComplex Carbohydrate Research Center, The University of Georgia, 315 Riverbend Road, Athens, Georgia 30602, USA.
Andre Venot
Omkar Dhamale
Geert-Jan Boons

Funding

New synthetic methods for the preparation of carbohydrate-based vaccinesR01GM065248 · NIGMS · UNIVERSITY OF GEORGIA (UGA) · PI BOONS, GEERT-JAN · 2004 to 2011
$3.0M
NIGMS NIH HHS 2R01GM065248NIGMS NIH HHS R01 GM065248
6 · The paper itself

Abstract

The modular synthesis of heparan sulfate fragments is greatly facilitated by employing an anomeric aminopentyl linker protected by a benzyloxycarbonyl group modified by a perfluorodecyl tag, which made it possible to purify highly polar intermediates by fluorous solid phase extraction. This tagging methodology made it also possible to perform repeated glycosylations to drive reactions to completion.

Indexed as

GlycosylationHeparan SulfateIndicators and ReagentsMolecular StructureOligosaccharidesSolid Phase ExtractionHeparan SulfateIndicators and ReagentsOligosaccharides

Identifiers

PMID23293947
PMCPMC3563243

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.