Evidence map›Paper›PMID 23293934›Full record

ArticleBiotechnic & histochemistry : official publication of the Biological Stain Commission2013

MicroRNAs as potential clinical biomarkers: emerging approaches for their detection.

S K Srivastava, A Bhardwaj, S J Leavesley, W E Grizzle, S Singh, A P Singh

Abstract read
In one paragraph

Article in Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  6. Article
  7. LINC00511 promotes gastric cancer cell growth by acting as a ceRNA.World journal of gastrointestinal oncology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S K SrivastavaMitchell Cancer Institute, University of South Alabama, Mobile.
A Bhardwaj
S J Leavesley
W E Grizzle
S Singh
A P Singh

Funding

MicroRNAs in Pancreatic CancerR03CA137513 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, AJAY PRATAP · 2009 to 2010
$148k
NCI NIH HHS CA137513NCI NIH HHS R03 CA137513
6 · The paper itself

Abstract

MicroRNAs (miRNAs) have emerged as novel post-transcriptional regulators of gene expression. These short non-coding RNAs are involved in diverse biological processes and their dysregulation is often observed under diseased conditions. Therefore, miRNAs hold great potential as clinical biomarkers of physiological and pathological states and extensive efforts are underway to develop efficient approaches for their detection. We review recent advances and discuss the promises and pitfalls of emerging methods of miRNA profiling and detection.

Indexed as

BiomarkersGene Expression Regulation, NeoplasticMicroRNAsNeoplasmsBiomarkersMicroRNAs

Identifiers

PMID23293934
PMCPMC4318494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.