Trial reportInternational journal of chronic obstructive pulmonary disease2013
Indacaterol improves daily physical activity in patients with chronic obstructive pulmonary disease.
Trial report in International journal of chronic obstructive pulmonary disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Indacaterol, a once-daily beta2-agonist, versus twice-daily beta₂-agonists or placebo for chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2015Pooled it
- The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease.The European respiratory journal · 2015Trial
- Influence of indacaterol on daily physical activity in patients with untreated chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2015Trial
- Indacaterol improves lung hyperinflation and physical activity in patients with moderate chronic obstructive pulmonary disease--a randomized, multicenter, double-blind, placebo-controlled study.BMC pulmonary medicine · 2014Trial
- Objective Measurement of Physical Activity and Sedentary Behavior in Patients with Chronic Obstructive Pulmonary Disease: Points to Keep in Mind during Evaluations.Journal of clinical medicine · 2023Review
- Computed Tomography Lung Density Analysis: An Imaging Biomarker Predicting Physical Inactivity in Chronic Obstructive Pulmonary Disease: A Pilot Study.Journal of clinical medicine · 2023Article
- Physical activity end-points in trials of chronic respiratory diseases: summary of evidence.ERJ open research · 2022Review
- Data Reproducibility and Effectiveness of Bronchodilators for Improving Physical Activity in COPD Patients.Journal of clinical medicine · 2020Review
- Simple standard equation for daily step count in Japanese patients with chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2019Observational
- Study Design of VESUTOAdvances in therapy · 2017Article
- A Modified Method for Examining the Walking Pattern and Pace of COPD Patients in a 6-min Walk Test Before and After the Inhalation of Procaterol.Internal medicine (Tokyo, Japan) · 2017Article
- Differences in physical activity according to mMRC grade in patients with COPD.International journal of chronic obstructive pulmonary disease · 2016Article
- A real-world evaluation of indacaterol and other bronchodilators in COPD: the INFLOW study.International journal of chronic obstructive pulmonary disease · 2015Observational
- Effects of pharmacologic treatment based on airflow limitation and breathlessness on daily physical activity in patients with chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2015Observational
- Physical Activity Monitoring in Patients with Chronic Obstructive Pulmonary Disease.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2014Review
- Efficacy of indacaterol on quality of life and pulmonary function in patients with COPD and inhaler device preferences.International journal of chronic obstructive pulmonary disease · 2014Article
- Improving physical activity in COPD: towards a new paradigm.Respiratory research · 2013Review
- The role of indacaterol for chronic obstructive pulmonary disease (COPD).Journal of thoracic disease · 2013Article
- Indacaterol: a comprehensive review.International journal of chronic obstructive pulmonary disease · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current mainstay of therapy for chronic obstructive pulmonary disease (COPD) is long-acting bronchodilators. To date, the effect of indacaterol, a β2-agonist, on activities of daily living in COPD patients is not well understood. The aim of this study was to evaluate the efficacy of indacaterol with regard to activities of daily living in patients with COPD.
methodsIn this nonrandomized open-label study, 23 patients with COPD were instructed to carry an accelerometer for 4 weeks without indacaterol therapy and then for another period of 4 weeks while receiving indacaterol therapy.
resultsThe number of steps, duration of moderate or greater physical activity, and energy expenditure were significantly increased after treatment with indacaterol compared with baseline data in all patients with COPD; the metabolic equivalent of task was also significantly enhanced after treatment with indacaterol.
conclusionThis study provides early evidence that indacaterol improves daily physical activity in patients with COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.