ArticleIndian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine2012
Study of Clinical Profile and Antibiotic Sensitivity Pattern in Culture-positive Typhoid Fever Cases.
Article in Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed, 13 citations in OpenAlex.
- Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5α.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015Article
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6 authors at 2 institutions in 1 country.
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Abstract
backgroundSalmonella enteric serotype Typhi has created a significant therapeutic problem as these strains have developed resistance to the commonly used antimicrobials for the treatment of typhoid fever.
objectivesTo assess the clinical profile and sensitivity patterns to anti-typhoid drugs. MATERIALS AND
methodsA retrospective analysis of 106 culture-positive typhoid cases admitted in a tertiary care hospital during the years 2005-2008.
resultsRecords of 106 patients were evaluated, 83 (78.3%) males and 23 (21.7%) females. Fever was present in all patients. Headache in 63 (59.4%) patients and generalized body ache in 53 (32.5%) patients were the most common symptoms, while spleenomegaly in 47 (44.3%) patients and hepatomegaly in 42 (39.6%) patients were the common presenting signs. A maximum sensitivity of 96.6% was observed with cephalosporins, whereas a resistance of 29.2% was seen with fluoroquinolones.
conclusionA high degree of sensitivity was noted to chloramphenicol, ampicillin and sulphonamides, showing a trend of roll-back of sensitivity to conventional antibiotics.
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