ArticleThe Plant cell2013
AUREOCHROME1a-mediated induction of the diatom-specific cyclin dsCYC2 controls the onset of cell division in diatoms (Phaeodactylum tricornutum).
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed, 144 citations in OpenAlex.
- Intermittent light enhances pigment production in the diatomMicrobiology spectrum · 2026Article
- The Ratio of Silicon to Chitin in Diatom Cell Walls Influences Their Resilience to Environmental Stress.Research (Washington, D.C.) · 2026Article
- The marine diatom Phaeodactylum tricornutum as a versatile bioproduction chassis: Current progress, challenges, and perspectives.Plant communications · 2025Review
- How to upgrade stolen organelles into permanent plastids: A comparative transcriptomic perspective.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Circadian regulation of key physiological processes by the RITMO1 clock protein in the marine diatom Phaeodactylum tricornutum.The New phytologist · 2025Article
- Photochemistry of Receptor-Bound Flavin Resolved in Living Human Cells by Infrared Spectroscopy.Journal of the American Chemical Society · 2025Article
- Localization of heme biosynthesis in the diatomFrontiers in plant science · 2025Article
- Article
- A rapid aureochrome opto-switch enables diatom acclimation to dynamic light.Nature communications · 2024Article
- A Knockout of the Photoreceptor PtAureo1a Results in Altered Diel Expression of Diatom Clock Components.Plants (Basel, Switzerland) · 2024Article
- More than a photoreceptor: aureochromes are intrinsic to the diatom light-regulated transcriptional network.Journal of experimental botany · 2024Article
- Identification of promoter targets by Aureochrome 1a in the diatom Phaeodactylum tricornutum.Journal of experimental botany · 2024Article
- Night-break treatment with blue and green lights regulates erect thallus formation in the brown algaFrontiers in plant science · 2024Article
- Transcriptome-based network analysis of cell cycle-related genes in response to blue and red light in maize.AoB PLANTS · 2023Article
- Genetic and physiological responses to light quality in a deep ocean ecotype of Ostreococcus, an ecologically important photosynthetic picoeukaryote.Journal of experimental botany · 2023Article
- Phenotypic Analysis and Molecular Characterization of Enlarged Cell Size Mutant inInternational journal of molecular sciences · 2023Article
- Transcriptomic and metabolic signatures of diatom plasticity to light fluctuations.Plant physiology · 2022Article
- Potential for the Production of Carotenoids of Interest in the Polar DiatomMarine drugs · 2022Article
- Aureochromes maintain polyunsaturated fatty acid content in Nannochloropsis oceanica.Plant physiology · 2022Article
- Trade-off between sex and growth in diatoms: Molecular mechanisms and demographic implications.Science advances · 2022Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell division in photosynthetic organisms is tightly regulated by light. Although the light dependency of the onset of the cell cycle has been well characterized in various phototrophs, little is known about the cellular signaling cascades connecting light perception to cell cycle activation and progression. Here, we demonstrate that diatom-specific cyclin 2 (dsCYC2) in Phaeodactylum tricornutum displays a transcriptional peak within 15 min after light exposure, long before the onset of cell division. The product of dsCYC2 binds to the cyclin-dependent kinase CDKA1 and can complement G1 cyclin-deficient yeast. Consistent with the role of dsCYC2 in controlling a G1-to-S light-dependent cell cycle checkpoint, dsCYC2 silencing decreases the rate of cell division in diatoms exposed to light-dark cycles but not to constant light. Transcriptional induction of dsCYC2 is triggered by blue light in a fluence rate-dependent manner. Consistent with this, dsCYC2 is a transcriptional target of the blue light sensor AUREOCHROME1a, which functions synergistically with the basic leucine zipper (bZIP) transcription factor bZIP10 to induce dsCYC2 transcription. The functional characterization of a cyclin whose transcription is controlled by light and whose activity connects light signaling to cell cycle progression contributes significantly to our understanding of the molecular mechanisms underlying light-dependent cell cycle onset in diatoms.
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