Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2013
The effect of individualized exercise interventions during treatment in pediatric patients with a malignant bone tumor.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cross-sectional Analysis of Functional and Structural Outcomes in Children, Adolescents and Young Adults Within Follow-up of Bone or Soft Tissue Sarcomas of the Lower Extremity
Prehabilitative Training in Children and Adolescents With Soft Tissue or Bone Sarcoma of the Lower Extremity - a Feasibility Study
Who cites it
22 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Nutrition and physical activity interventions delivered to children and young people during cancer treatment: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Supervised Physical Activity Interventions in Children and Adolescents with Cancer Undergoing Treatment-A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Physical therapy interventions, other than general physical exercise interventions, in children and adolescents before, during and following treatment for cancer.The Cochrane database of systematic reviews · 2021Pooled it
- Parental involvement in exercise and diet interventions for childhood cancer survivors: a systematic review.Pediatric research · 2016Pooled it
- Physical exercise training interventions for children and young adults during and after treatment for childhood cancer.The Cochrane database of systematic reviews · 2016Pooled it
- Remotely delivered resistance training program in adult sarcoma survivors: a pilot study.BMC cancer · 2026Trial
- Effects of an Exercise Intervention on Gait Function in Young Survivors of Osteosarcoma with Megaendoprosthesis of the Lower Extremity-Results from the Pilot Randomized Controlled Trial proGAIT.Current oncology (Toronto, Ont.) · 2022Trial
- Longitudinal Functional Outcomes Among Survivors of Childhood Lower Extremity Osteosarcoma.Cancers · 2026Article
- Exploring Anthracycline-Induced Cardiotoxicity from the Perspective of Protein Quality Control.Reviews in cardiovascular medicine · 2024Review
- Effects of Exercise and Physical Activity Levels on Childhood Cancer: An Umbrella Review.Healthcare (Basel, Switzerland) · 2023Review
- Article
- Effects of strength exercise interventions on activities of daily living, motor performance, and physical activity in children and adolescents with leukemia or non-Hodgkin lymphoma: Results from the randomized controlled ActiveADL Study.Frontiers in pediatrics · 2022Article
- Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer (INTERACT): Study Protocol for a Multicenter, Two-Arm Parallel-Group Randomized Controlled Superiority Trial.Frontiers in pediatrics · 2022Article
- Promoting positive physical activity behaviors for children and adolescents undergoing acute cancer treatment: Development of the CanMOVE intervention using the Behavior Change Wheel.Frontiers in pediatrics · 2022Article
- Exercise and Childhood Cancer-A Historical Review.Cancers · 2021Review
- Exercise and Physical Activity in Patients with Osteosarcoma and Survivors.Advances in experimental medicine and biology · 2020Review
- Dietary and Exercise Interventions for Pediatric Oncology Patients: The Way Forward.Journal of the National Cancer Institute. Monographs · 2019Review
- Early Nutrition and Physical Activity Interventions in Childhood Cancer Survivors.Current obesity reports · 2017Review
- The Practice of Physical Activity in the Setting of Lower-Extremities Sarcomas: A First Step toward Clinical Optimization.Frontiers in physiology · 2017Article
- Objectively measured versus self-reported physical activity in children and adolescents with cancer.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile research on exercise interventions during anticancer treatment is well-established in adults, only very few studies exist in children. However, pediatric patients experience great limitations to being physically active, and appropriate interventions are desired. PROCEDURE: The present study aimed at investigating the effects of individualized exercise interventions during inpatient stays on pediatric patients with a malignant bone tumor. The parameter of interest was physical activity (PA). Patients' PA during home stays was assessed 6 weeks as well as 3, 6, 12, and 18 months post-surgery. Patients were distinguished into an intervention group and a control group. All patients received endoprosthetic replacement of the affected bone in the same institution.
resultsA constant increase in all PA parameters was observed during follow-up. Exercise interventions were possible and appeared worthwhile. The intervention group showed better PA results at all measurements; however, no significant differences between groups were found. Furthermore, differences decreased especially after the cessation of the intervention. General problems in reaching appropriate power and compliance were observed.
conclusionsIndividualized exercise interventions in pediatric bone tumor patients are possible and appear to be beneficial. Such interventions should be implemented in adjuvant care; however, future research is needed to understand more about the effects of different interventions.
Indexed as
Identifiers
23292667What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.