ArticleJournal of magnetic resonance imaging : JMRI2013
Automated T(2) * measurements using supplementary field mapping to assess cardiac iron content.
Article in Journal of magnetic resonance imaging : JMRI, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- T2* assessment of the three coronary artery territories of the left ventricular wall by different monoexponential truncation methods.Magma (New York, N.Y.) · 2022Article
- Cardiac TJournal of magnetic resonance imaging : JMRI · 2020Review
- Fast quantitative parameter maps without fitting: Integration yields accurate mono-exponential signal decay rates.Magnetic resonance in medicine · 2018Article
- Semi-automated myocardial segmentation of bright blood multi-gradient echo images improves reproducibility of myocardial contours and T2* determination.Magma (New York, N.Y.) · 2017Article
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Authors and funding
6 authors.
Funding
Abstract
purposeTo develop and evaluate an algorithm that automatically identifies high-susceptibility areas and excludes them from T(2) * measurements in the left ventricle (LV) for myocardial iron measurements. MATERIALS AND
methodsAn autoregressive moving average (ARMA) model was implemented on multigradient echo scans of 24 patients (age range 3-45 years, 10 male/14 female). Voxels with relatively high susceptibility (>3 Hz/mm) were flagged and deselected from the T(2) * calculations for iron quantification. The mean, standard deviation, and coefficient of variation (CoV) of the ARMA-defined region were compared to the CoV of four distinct regions of the LV and the entire LV using a Student's t-test (α = 0.05).
resultsThe CoV of T(2) * values obtained by the ARMA method are comparable with that in the interventricular septum (IS), where susceptibility was the lowest (CoV = 0.31). The ARMA method provides a greater area (51.9 ± 13.7% of the LV) to measure T(2) * than that using the IS alone (21.1 ± 3.4%, P < 0.0001). Areas where low susceptibility are measured corroborate with areas reported in previous studies that investigated T(2) * variations throughout the LV.
conclusionAn automated method to measure T(2) * relaxation in the LV with minimal effects from susceptibility has been developed. Variability is reduced while covering more regions for cardiac T2 * calculation.
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