ArticleJournal of health and social behavior2013
Genetic sensitivity to peer behaviors: 5HTTLPR, smoking, and alcohol consumption.
Article in Journal of health and social behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Genotype × Environment Interaction in Smoking Behaviors: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017Pooled it
- Gene-by-peer-environment interaction effects on cigarette, alcohol, and marijuana use among US high school students of European Ancestry.Social science & medicine (1982) · 2022Article
- Emotional self-regulation, impulsivity, 5-HTTLPR and tobacco use behavior among psychiatric inpatients.Journal of affective disorders · 2022Article
- Review
- Genome-wide stress sensitivity moderates the stress-depression relationship in a nationally representative sample of adults.Scientific reports · 2021Article
- Evaluating the Continued Integration of Genetics into Medical Sociology.Journal of health and social behavior · 2021Article
- Cohort Profile: The National Longitudinal Study of Adolescent to Adult Health (Add Health).International journal of epidemiology · 2019Article
- A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults.The American journal on addictions · 2018Review
- The Biosocial Approach to Human Development, Behavior, and Health Across the Life Course.The Russell Sage Foundation journal of the social sciences : RSF · 2018Article
- Review: Environmental influences on alcohol use: Informing research on the joint effects of genes and the environment in diverse U.S. populations.The American journal on addictions · 2017Review
- The Social Determinants of Chronic Disease.American journal of preventive medicine · 2017Review
- Opportunities and challenges of big data for the social sciences: The case of genomic data.Social science research · 2016Article
- Narrative review of genes, environment, and cigarettes.Annals of medicine · 2016Review
- Parental and adolescent health behaviors and pathways to adulthood.Social science research · 2016Article
- Differential susceptibility to environmental influences: Interactions between child temperament and parenting in adolescent alcohol use.Development and psychopathology · 2016Article
- Cohort Effects in the Genetic Influence on Smoking.Behavior genetics · 2016Article
- Genetic Polymorphism in the Promoter Region of Serotonin Transporter: Implications for Ethanol Abuse in Children and Adolescents.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2016Article
- Genome-Wide Estimates of Heritability for Social Demographic Outcomes.Biodemography and social biology · 2016Article
- Neighborhood crime and depressive symptoms among African American women: Genetic moderation and epigenetic mediation of effects.Social science & medicine (1982) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We investigate whether the serotonin transporter-linked polymorphic region (5HTTLPR), a gene associated with environmental sensitivity, moderates the association between smoking and drinking patterns at adolescents' schools and their corresponding risk for smoking and drinking themselves. Drawing on the school-based design of the National Longitudinal Study of Adolescent Health in conjunction with molecular genetic data for roughly 15,000 respondents (including over 2,000 sibling pairs), we show that adolescents smoke more cigarettes and consume more alcohol when attending schools with elevated rates of tobacco and alcohol use. More important, an individual's susceptibility to school-level patterns of smoking or drinking is conditional on the number of short alleles he or she has in 5HTTLPR. Overall, the findings demonstrate the utility of the differential susceptibility framework for medical sociology by suggesting that health behaviors reflect interactions between genetic factors and the prevalence of these behaviors in a person's context.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.