Trial reportJournal of neurology2013
Natural course of positional down-beating nystagmus of peripheral origin.
Trial report in Journal of neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Clinical characteristics and therapeutic outcomes of 120 patients with positional down-beat nystagmus (pDBN) with negative brain MRI.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Revisiting BPPV: Incidence and Behavior of Atypical Variants.Audiology research · 2025Article
- Clinical spectrum of positional downbeat nystagmus: a diagnostic approach.Journal of neurology · 2025Review
- Poly-symptomatology of chronic multi-canalicular benign paroxysmal positional vertigo: a deductive, inductive, and abductive narrative review.Frontiers in neurology · 2025Review
- Anterior Canal BPPV- A Rare Form of Vertical Canaloliathiasis: Series of 11 Cases.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Central positional nystagmus: an update.Journal of neurology · 2022Review
- Atypical Positional Vertigo: Definition, Causes, and Mechanisms.Audiology research · 2022Review
- Case report: Atypical patterns of nystagmus suggest posterior canal cupulolithiasis and short-arm canalithiasis.Frontiers in neurology · 2022Article
- Complex nystagmus in traumatic benign paroxysmal positional vertigo: A case study on the critical value of knowing semicircular canal excitation and inhibition patterns.Journal of otology · 2021Article
- Less common forms of posterior canal benign paroxysmal positional vertigo.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Article
- Clinical and VNG Features in Anterior Canal BPPV-An Analysis of 13 Cases.Frontiers in neurology · 2021Article
- Feasibility of Using the Video-Head Impulse Test to Detect the Involved Canal in Benign Paroxysmal Positional Vertigo Presenting With Positional Downbeat Nystagmus.Frontiers in neurology · 2020Article
- Benign Positional Paroxysmal Vertigo Treatment: a Practical Update.Current treatment options in neurology · 2019Review
- Incidence and Clinical Significance of Positional Downbeat Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo.Journal of clinical neurology (Seoul, Korea) · 2019Article
- Treatment of benign paroxysmal positional vertigo. A clinical review.Journal of otology · 2017Review
- Diagnosis and Treatment of Anterior-Canal Benign Paroxysmal Positional Vertigo: A Systematic Review.Journal of clinical neurology (Seoul, Korea) · 2015Article
- Approach to dizziness in the emergency department.Clinical and experimental emergency medicine · 2015Review
- A New Variant of Posterior Canal Benign Paroxysmal Positional Vertigo: A Nonampullary or Common Crus Canalolithiasis.Case reports in otolaryngology · 2015Article
- Repositioning maneuvers for benign paroxysmal positional vertigo.Current treatment options in neurology · 2014Article
- Anterior canal BPPV and apogeotropic posterior canal BPPV: two rare forms of vertical canalolithiasis.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess the natural course of positional down-beating nystagmus (pDBN) and vertigo in patients with no evidence of central nervous system involvement and of presumed peripheral origin. Fifty-three patients with pDBN had a complete otoneurological examination. All subjects, apart from three (excluded from the study), showed no additional neurological signs and normal brain imaging. Patients were randomly assigned to two groups: with or without treatment with exercise. Patients were seen again after 24 h, and then weekly for up to 6 months. Forty-seven patients (94%) showed pDBN in the straight head-hanging position and in a Dix-Hallpike position. A torsional component was detected in 17 patients (34%). The mean latency and duration of pDBN was 4.7 ± 5 s and 40.1 ± 22 s, respectively. After 2 weeks, only 12 patients (24%) still had pDBN and all but one patient had recovered by 1 month. Twenty patients (40%) were diagnosed with a typical posterior canal benign paroxysmal positional vertigo (PC BPPV) before or after pDBN. This study assessed for the first time the natural course of presumed peripheral pDBN, which was characterized by a spontaneous remission in 24 patients in the first week and in 49 patients within 4 weeks. pDBN is much more common than previously suggested, with about the same frequency as lateral canal BPPV. Furthermore, the clinical characteristics of pDBN have been highlighted, as well as its possible relationship to PC BPPV.
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Registered trials
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