Evidence map›Paper›PMID 23291664›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2013

Prognosis of patients with atrial fibrillation undergoing percutaneous coronary intervention receiving drug eluting stents.

Peter Bramlage, Alessandro Cuneo, Uwe Zeymer, Matthias Hochadel, Gert Richardt, Sigmund Silber, Jochen Senges, Christoph A Nienaber, Ulrich Tebbe, Karl-Heinz Kuck

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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Large-scale experience with an anchorless vascular closure device in a real-life clinical setting.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Atrial fibrillation and long-term sports practice: epidemiology and mechanisms.Clinical research in cardiology : official journal of the German Cardiac Society · 2015
    Review
  14. Article
  15. Observational
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Peter BramlageInstitut für Pharmakologie und präventive Medizin, Mahlow, Germany.
Alessandro Cuneo
Uwe Zeymer
Matthias Hochadel
Gert Richardt
Sigmund Silber
Jochen Senges
Christoph A Nienaber
Ulrich Tebbe
Karl-Heinz Kuck
Stiftung Institut für Herzinfarktforschung · DEAsklepios Klinik St. Georg · DEKlinikum Lippe · DEMahlo (Germany) · DESegeberger Kliniken · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is increasingly prevalent in elderly patients and adversely affects clinical outcomes after coronary artery bypass grafting, non-cardiac surgery or myocardial infarction. Aim of the present analysis was to investigate the prognostic impact of AF in patients undergoing drug eluting stent (DES) implantation during a 1-year follow-up. PATIENTS AND

methods5,772 consecutive patients undergoing percutaneous coronary intervention were enrolled into the German Drug Eluting Stent Registry (DES.DE) and were followed for 12 months. Of these 455 had AF and 5,317 in sinus rhythm served as controls. Univariate and multivariate logistic regression analyses were used to determine the risk of major adverse cardiac and cerebrovascular events (MACCE) and bleeding complications.

resultsPatients with AF were older (71.3 ± 7.6 vs. 64.7 ± 10.5 years) and had a higher prevalence of diabetes, hypertension, renal insufficiency as well as more prior bypass surgery, stroke and peripheral arterial disease. Cardiogenic shock (2.9 vs. 1.4 %; p < 0.05), left ventricular ejection fraction ≤40 % (21.0 vs. 11.4 %; p < 0.0001) and triple vessel disease (44.4 vs. 37.9 %; p < 0.01) were more frequent in patients with AF than in controls. MACCE (OR 2.08, 95 % CI 1.56-2.77), total mortality (OR 3.27, 95 % CI 2.32-4.62) and non-fatal stroke (OR 2.03, 95 % CI 1.03-4.00) as well as bleeding complications (OR 1.88, 95 % CI 1.13-3.12) during the 1-year follow-up were more frequent in patients with AF (univariate analysis). In multivariate analyses adjusting for covariates determined to be relevant at baseline, the risk for total mortality remained elevated (OR 1.63, 95 % CI 1.05-2.52).

conclusionsAF is an important predictor of long-term mortality in patients undergoing DES implantation.

Indexed as

Drug-Eluting StentsAgedAge FactorsAtrial FibrillationCardiovascular DiseasesFollow-Up StudiesGermanyHemorrhageHumansLogistic ModelsMiddle AgedMultivariate AnalysisPercutaneous Coronary InterventionPrognosisRegistriesStroke

Identifiers

PMID23291664
OpenAlexW2079681961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.