SynthesisNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2013
A systematic review of the relationships between craving and smoking cessation.
Synthesis in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association of Drug Cues and Craving With Drug Use and Relapse: A Systematic Review and Meta-analysis.JAMA psychiatry · 2022Pooled it
- Food cue reactivity and craving predict eating and weight gain: a meta-analytic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016Pooled it
- Effects of experimental negative affect manipulations on ad libitum smoking: a meta-analysis.Addiction (Abingdon, England) · 2015Pooled it
- The clinical significance of drug craving.Annals of the New York Academy of Sciences · 2012Pooled it
- Do lab-based assessments of pretreatment smoking reinforcement and cue-specific craving predict smoking cessation with varenicline?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Trial
- A randomized controlled experiment testing the use of virtual reality to trigger cigarette craving in people who smoke.Scientific reports · 2024Trial
- Relationships Between the Nicotine Metabolite Ratio and Laboratory Assessments of Smoking Reinforcement and Craving Among Adults in a Smoking Cessation Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Trial
- Bayesian continuous-time hidden Markov models with covariate selection for intensive longitudinal data with measurement error.Psychological methods · 2023Trial
- A Brief Motivational Intervention Differentially Reduces Sugar-sweetened Beverage (SSB) Consumption.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Trial
- Craving to Quit: A Randomized Controlled Trial of Smartphone App-Based Mindfulness Training for Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Trial
- Evaluating the temporal relationships between withdrawal symptoms and smoking relapse.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019Trial
- Momentary changes in craving predict smoking lapse behavior: a laboratory study.Psychopharmacology · 2018Trial
- Visceral States Call for Visceral Measures: Verbal Overshadowing of Hunger Ratings Across Assessment Modalities.Assessment · 2018Trial
- Exenatide once weekly for smoking cessation: study protocol for a randomized clinical trial.Medicine · 2018Trial
- Smoking Urges During Treatment and Long-Term Cessation among Low-Income African Americans.Ethnicity & disease · 2017Trial
- Evaluating Nicotine Craving, Withdrawal, and Substance Use as Mediators of Smoking Cessation in Cocaine- and Methamphetamine-Dependent Patients.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016Trial
- Time-varying effects of a text-based smoking cessation intervention for urban adolescents.Drug and alcohol dependence · 2015Trial
- Positive smoking outcome expectancies mediate the association between negative affect and smoking urge among women during a quit attempt.Experimental and clinical psychopharmacology · 2014Trial
- Perceived medication assignment during a placebo-controlled laboratory study of varenicline: temporal associations of treatment expectancies with smoking-related outcomes.Psychopharmacology · 2014Trial
- Decline in cue-provoked craving during cue exposure therapy for smoking cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014Trial
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
introductionCraving is often portrayed as a defining feature of addiction, but the role of craving in the addictive process is controversial. Particularly contentious is the extent to which drug craving predicts subsequent relapse.
methodsThis review synthesizes findings from 62 smoking cessation studies published through December 2011. Eligible studies measured craving for cigarettes in treatment-seeking smokers and related this to subsequent smoking status. The relationships of general craving and cue-specific craving with treatment outcome were examined separately. Further, analyses that related general craving to smoking status were divided into those that used craving data collected before the quit attempt, after the quit attempt, and those that used change in craving over time as a predictor.
resultsResults across studies revealed a total of 198 indices of association with 94 (47%) of these being significant. In general, the findings indicated (a) there were only a few cases of significant associations between craving collected as part of cue-reactivity studies and treatment outcome, (b) postquit craving was a stronger predictor of treatment outcome than prequit craving, and (c) several moderators likely influence the relationship between craving and cessation outcome.
conclusionsThe overall results suggest that craving is not a necessary condition of relapse. In addition, inconsistent relationships between craving and treatment outcome call into question the value of craving as a target of treatment and underscore limitations in the prognostic utility of craving.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.