Evidence map›Paper›PMID 23290746›Full record

ReviewFertility and sterility2013

Biomarkers for ectopic pregnancy and pregnancy of unknown location.

Suneeta Senapati, Kurt T Barnhart

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Fertility and sterility, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04176549 unknown statusnot on this mapstarted 2019, after this paper: background citation

The Assessment of Biomarkers in Ectopic Pregnancy

TypeobservationalSponsorImperial College LondonRan2019 to 2025Enrolled200ConditionsEctopic PregnancyArmsManagement of Ectopic Pregnancy, Management of termination of pregnancy, Elective management of gynaecology patients
NCT05591599 unknown statusnot on this mapstarted 2022, after this paper: background citation

Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies

TypeobservationalSponsorMỹ Đức HospitalRan2022 to 2025Enrolled407ConditionsTubal PregnancyArmscalponin 2
3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Ectopic pregnancy.Nature reviews. Disease primers · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Validation of a multiple marker test for early pregnancy outcome prediction.Journal of assisted reproduction and genetics · 2023
    Article
  7. Article
  8. Article
  9. Pregnancy of unknown location.Clinics (Sao Paulo, Brazil) · 2019
    Article
  10. Gestational hormone trajectories and early pregnancy failure: a reassessment.Reproductive biology and endocrinology : RB&E · 2018
    Article
  11. Article
  12. Article
  13. Factors to consider in pregnancy of unknown location.Women's health (London, England) · 2017
    Review
  14. Analysis of ectopic pregnancies admitted to emergency department.Turkish journal of emergency medicine · 2015
    Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suneeta SenapatiDepartment of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kurt T Barnhart

Funding

REPRODUCTIVE EPIDEMIOLOGY TRAINING GRANTT32HD007440 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BARNHART, KURT T · 1996 to 2020
$7.5M
Development of a serum biosignature for ectopic pregnancy.R01HD076279 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BARNHART, KURT T · 2014 to 2018
$3.4M
Midcareer investigator award in patient oriented researchK24HD060687 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BARNHART, KURT T · 2009 to 2014
$956k
NICHD NIH HHS K24 HD060687NICHD NIH HHS K24HD060687NICHD NIH HHS R01 HD076279NICHD NIH HHS T32 HD007440NICHD NIH HHS T32HD7440-16
6 · The paper itself

Abstract

Early pregnancy failure is the most common complication of pregnancy, and 1% to 2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum and plasma biomarkers for ectopic pregnancy have been investigated independently and in combination. The following is a review of the state of biomarker discovery and development for ectopic pregnancy and pregnancy of unknown location.

Indexed as

BiomarkersEndometriumFemaleHumansPregnancyPregnancy, EctopicPregnancy Trimester, FirstProteomicsBiomarkers

Identifiers

PMID23290746
PMCPMC3602335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.