Evidence map›Paper›PMID 23290463›Full record

ReviewTrends in cardiovascular medicine2013

Visualizing novel concepts of cardiovascular calcification.

Jesper Hjortnaes, Sophie E P New, Elena Aikawa

Abstract readReview
In one paragraph

Review in Trends in cardiovascular medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Potential of Blood Speckle Imaging andJournal of cardiovascular imaging · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. IL-1β in atherosclerotic vascular calcification: From bench to bedside.International journal of biological sciences · 2021
    Review
  13. Article
  14. Article
  15. Review
  16. Arterial Inflammation Detected WithArthritis & rheumatology (Hoboken, N.J.) · 2018
    Article
  17. Review
  18. Calcific aortic stenosis.Nature reviews. Disease primers · 2016
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jesper HjortnaesCardiovascular Medicine, Brigham & Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, NRB741J, Boston, MA 02115, USA.
Sophie E P New
Elena Aikawa

Funding

Aortic valve microcalcificationR01HL114805 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI AIKAWA, ELENA · 2012 to 2016
$2.1M
NHLBI NIH HHS R01 HL114805
6 · The paper itself

Abstract

Cardiovascular calcification is currently viewed as an active disease process similar to embryonic bone formation. Cardiovascular calcification mainly affects the aortic valve and arteries and is associated with increased mortality risk. Aortic valve and arterial calcification share similar risk factors, including age, gender, diabetes, chronic renal disease, and smoking. However, the exact cellular and molecular mechanism of cardiovascular calcification is unknown. Late-stage cardiovascular calcification can be visualized with conventional imaging modalities such as echocardiography and computed tomography. However, these modalities are limited in their ability to detect the development of early calcification and the progression of calcification until advanced tissue mineralization is apparent. Due to the subsequent late diagnosis of cardiovascular calcification, treatment is usually comprised of invasive interventions such as surgery. The need to understand the process of calcification is therefore warranted and requires new imaging modalities which are able to visualize early cardiovascular calcification. This review focuses on the use of new imaging techniques to visualize novel concepts of cardiovascular calcification.

Indexed as

Diagnostic ImagingAnimalsCalcinosisCardiomyopathiesEarly DiagnosisEchocardiographyEndothelial CellsHumansInflammation MediatorsMolecular ImagingPredictive Value of TestsPrognosisTomography, X-Ray ComputedVascular CalcificationInflammation Mediators

Identifiers

PMID23290463
PMCPMC3626075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.