ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2013
Magnitude and causes of bias among family caregivers rating Alzheimer disease patients.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Intranasal administration of stem cells and their derivatives for neurological and respiratory disorders: a systematic review of human clinical trials.Frontiers in aging neuroscience · 2026Pooled it
- Development of the Observable Well-Being in Living With Dementia-Scale.American journal of Alzheimer's disease and other dementiasPooled it
- Measures used to evaluate psychosocial interventions in dementia care: A narrative review and synthesis.Journal of Alzheimer's disease : JAD · 2026Review
- The design of embedded pragmatic clinical trials: methodological developments and statistical lessons learned from the first cycle of the NIA IMPACT collaboratory.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Wearable monitoring during music-based interventions in dementia: physiological and behavioral observations from a pilot study.Frontiers in human neuroscience · 2026Article
- Harmonizing self-reported and free text medication data: a reproducible pipeline for gerontological research.BMC medical informatics and decision making · 2025Article
- Family cohesion and conflict in the context of adult children and parents living with early-stage cognitive impairment.Aging & mental health · 2025Observational
- Behavioural changes in frontotemporal dementia and their cognitive and neuroanatomical correlates.Brain : a journal of neurology · 2025Article
- Concurrent Validity of Performance-Based Measures of Daily Functioning with Cognitive Measures and Informant Reported Everyday Functioning.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Self- versus caregiver-reported apathy across neurological disorders.Brain communications · 2025Article
- Therapeutic Potential of Porcine Brain-Derived Peptide Mixture (PBDP) in Alzheimer's Disease: An Exploratory Study on Quantitative Electroencephalography (qEEG) Changes.Neuropsychiatric disease and treatment · 2025Article
- Emotion regulation in people living with dementia and their spouses: the role of neuropsychiatric symptoms.Aging & mental health · 2024Article
- Potential impact of the COVID-19 pandemic on everyday preferences for persons with cognitive impairment.International psychogeriatrics · 2024Article
- Assessing Patients and Care Partner Ratings of Communication-Related Participation Restrictions: Insights From Degenerative Disease.American journal of speech-language pathology · 2023Article
- Perceptions of function and recovery among persons with stroke and care partners.Rehabilitation psychology · 2022Article
- Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners.International journal of geriatric psychiatry · 2022Article
- The role of dyadic cognitive report and subjective cognitive decline in early ADRD clinical research and trials: Current knowledge, gaps, and recommendations.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Reconsidering Gold Standards for Surrogate Decision Making for People with Dementia.The Psychiatric clinics of North America · 2021Review
- Poor Disgust Suppression Is Associated with Increased Anxiety in Caregivers of People with Neurodegenerative Disease.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021Article
- Assessing Momentary Well-Being in People Living With Dementia: A Systematic Review of Observational Instruments.Frontiers in psychology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveFamily caregivers generally underestimate the health and well-being of Alzheimer disease (AD) patients when compared to patients' self-assessments. The goals of this study were to identify caregiver, patient, and contextual factors associated with caregiver rating bias.
methodsOne hundred five patients with AD, along with their family caregivers, were assessed twice by trained interviewers 1-year apart. In separate interviews, caregivers were asked to rate the quality of life and suffering of their patient relative, and patients provided self-ratings using the same structured instruments. Multivariate cross-sectional and longitudinal analyses were used to identify predictors of caregiver-patient discrepancies.
resultsCaregivers consistently reported significantly higher levels of suffering and lower levels of quality of life than patients. Caregiver psychological well-being and health status accounted for a substantial portion of the difference in caregiver and patient ratings in both cross-sectional and longitudinal analyses. Caregiver depression and burden were consistently positively associated with the magnitude of caregiver-patient discrepancy, and caregiver health status was negatively associated with the size of the discrepancy.
conclusionsCaregiver assessments of dementia patients may determine the type and frequency of treatment received by the patient, and caregivers' ability to reliably detect change in patient status can play a critical role in evaluating the efficacy of therapeutic interventions and pharmacologic agents. Clinicians and researchers working with dementia patients who rely on caregiver reports of patient status should be sensitive to the health and well-being of the caregiver and recognize that caregiver assessments may be negatively biased when the caregiver's own well-being is compromised.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.