ArticleEpilepsy research2013
Effects of transcranial focal electrical stimulation via tripolar concentric ring electrodes on pentylenetetrazole-induced seizures in rats.
Article in Epilepsy research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Tripolar concentric ring electrodes for capturing localised electroencephalography signals during sleep.Journal of sleep research · 2024Article
- Workshops of the Eighth International Brain-Computer Interface Meeting: BCIs: The Next Frontier.Brain computer interfaces (Abingdon, England) · 2022Article
- Investigating the Feasibility of Epicranial Cortical Stimulation Using Concentric-Ring Electrodes: A Novel Minimally Invasive Neuromodulation Method.Frontiers in neuroscience · 2019Article
- Safety of the Transcranial Focal Electrical Stimulation via Tripolar Concentric Ring Electrodes for Hippocampal CA3 Subregion Neurons in Rats.Journal of healthcare engineering · 2017Article
- Improving the Accuracy of Laplacian Estimation with Novel Variable Inter-Ring Distances Concentric Ring Electrodes.Sensors (Basel, Switzerland) · 2016Article
- Improving the accuracy of Laplacian estimation with novel multipolar concentric ring electrodes.Measurement : journal of the International Measurement Confederation · 2016Article
- Acute seizure suppression by transcranial direct current stimulation in rats.Annals of clinical and translational neurology · 2015Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo study the effects of noninvasive transcranial focal electrical stimulation (TFS) via tripolar concentric ring electrodes (TCRE) on the electrographic and behavioral activity from pentylenetetrazole (PTZ)-induced seizures in rats.
methodsThe TCREs were attached to the rat scalp. PTZ was administered and, after the first myoclonic jerk was observed, TFS was applied to the TFS treated group. The electroencephalogram (EEG) and behavioral activity were recorded and studied.
resultsIn the case of the TFS treated group, after TFS, there was a significant (p=0.001) decrease in power compared to the control group in delta, theta, and alpha frequency bands. The number of myoclonic jerks was significantly different (p=0.002) with median of 22 and 4.5 for the control group and the TFS treated groups, respectively. The duration of myoclonic activity was also significantly different (p=0.031) with median of 17.56 min for the control group versus 8.63 min for the TFS treated group. At the same time there was no significant difference in seizure onset latency and maximal behavioral seizure activity score between control and TFS treated groups.
conclusionsTFS via TCREs interrupted PTZ-induced seizures and electrographic activity was reduced toward the "baseline." The significantly reduced electrographic power, number of myoclonic jerks, and duration of myoclonic activity of PTZ-induced seizures suggests that TFS may have an anticonvulsant effect.
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