ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2013
Barriers to cancer clinical trial participation among American Indian and Alaska Native tribal college students.
Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Racial and ethnic disparities in enrollment for clinical trials of poly (ADP-ribose) polymerase (PARP) inhibitors in breast cancer treatment.Cancer causes & control : CCC · 2026Pooled it
- Smoking Cessation Interventions in Indigenous North Americans: A Meta-Narrative Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Pooled it
- A systematic literature review of Native American and Pacific Islanders' perspectives on health data privacy in the United States.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Barriers and facilitators to recruitment of rural patients to cancer clinical trials.Proceedings (Baylor University. Medical Center) · 2025Review
- Qualitative Study of Health Care Professional Perspectives on Recruiting Minority Patients in Cancer Trials.Health equity · 2025Article
- Using Bayesian hierarchical models for controlled post hoc subgroup analysis of clinical trials: application to smoking cessation treatment in American Indians and Alaska Natives.Journal of biopharmaceutical statistics · 2024Article
- Knowledge and Attitudes of Guam Residents towards Cancer Clinical Trial Participation.International journal of environmental research and public health · 2022Article
- Designing Inclusive HPV Cancer Vaccines and Increasing Uptake among Native Americans-A Cultural Perspective Review.Current oncology (Toronto, Ont.) · 2021Review
- Community Perspectives on Communicating About Precision Medicine in an Alaska Native Tribal Health Care System.Frontiers in communication · 2020Article
- Race- and Sex-Based Disparities in Alzheimer's Disease Clinical Trial Enrollment in the United States and Canada: An Indigenous Perspective.Journal of Alzheimer's disease reports · 2020Review
- Data Management in Health-Related Research Involving Indigenous Communities in the United States and Canada: A Scoping Review.Frontiers in genetics · 2019Article
- Perceptions of and decision making about clinical trials in adolescent and young adults with Cancer: a qualitative analysis.BMC cancer · 2018Article
- The ConNECT Framework: a model for advancing behavioral medicine science and practice to foster health equity.Journal of behavioral medicine · 2017Article
- Factors affecting patient participation in clinical trials in Ireland: A narrative review.Contemporary clinical trials communications · 2016Article
- Adolescent and young adult patients with cancer: a milieu of unique features.Nature reviews. Clinical oncology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeAmerican Indians and Alaska Natives (AIs/ANs) have some of the highest cancer-related mortality rates of all US racial and ethnic groups, but they are underrepresented in clinical trials. We sought to identify factors that influence willingness to participate in cancer clinical trials among AI/AN tribal college students, and to compare attitudes toward clinical trial participation among these students with attitudes among older AI/AN adults.
methodsQuestionnaire data from 489 AI/AN tribal college students were collected and analyzed along with previously collected data from 112 older AI/AN adults. We examined 10 factors that influenced participation in the tribal college sample, and using chi-square analysis and these 10 factors, we compared attitudes toward research participation among 3 groups defined by age: students younger than 40, students 40 and older, and nonstudent adults 40 and older.
findingsAbout 80% of students were willing to participate if the study would lead to new treatments or help others with cancer in their community, the study doctor had experience treating AI/AN patients, and they received payment. Older nonstudent adults were less likely to participate on the basis of the doctor's expertise than were students (73% vs 84%, P = .007), or if the study was conducted 50 miles away (24% vs 41%, P= .001).
conclusionsFinding high rates of willingness to participate is an important first step in increasing participation of AIs/ANs in clinical trials. More information is needed on whether these attitudes influence actual behavior when opportunities to participate become available.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.