Evidence map›Paper›PMID 23287990›Full record

ArticleBritish journal of cancer2013

Early mortality from colorectal cancer in England: a retrospective observational study of the factors associated with death in the first year after diagnosis.

A Downing, A Aravani, U Macleod, S Oliver, P J Finan, J D Thomas, P Quirke, J R Wilkinson, E J A Morris

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In one paragraph

Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

A DowningCancer Epidemiology Group, Centre for Epidemiology and Biostatistics, University of Leeds, Level 6, Bexley Wing, St James's Institute of Oncology, St James's University Hospital, Leeds LS9 7TF, UK. a.downing@leeds.ac.uk
A Aravani
U Macleod
S Oliver
P J Finan
J D Thomas
P Quirke
J R Wilkinson
E J A Morris
St James's University Hospital · GBUniversity of Leeds · GBUniversity of Hull · GBWellcome Trust · GB

Funding

Cancer Research UK 9805Cancer Research UK C23434/A9805
6 · The paper itself

Abstract

backgroundThe United Kingdom performs poorly in international comparisons of colorectal cancer survival with much of the deficit owing to high numbers of deaths close to the time of diagnosis. This retrospective cohort study investigates the patient, tumour and treatment characteristics of those who die in the first year after diagnosis of their disease.

methodsPatients diagnosed with colon (n=65,733) or rectal (n=26,123) cancer in England between 2006 and 2008 were identified in the National Cancer Data Repository. Multivariable logistic regression was used to investigate the odds of death within 1 month, 1-3 months and 3-12 months after diagnosis.

resultsIn all, 11.5% of colon and 5.4% of rectal cancer patients died within a month of diagnosis: this proportion decreased significantly over the study period. For both cancer sites, older age, stage at diagnosis, deprivation and emergency presentation were associated with early death. Individuals who died shortly after diagnosis were also more likely to have missing data about important prognostic factors such as disease stage and treatment.

conclusionUsing routinely collected data, at no inconvenience to patients, we have identified some important areas relating to early deaths from colorectal cancer, which merit further research.

Indexed as

Age FactorsColonic NeoplasmsFemaleFollow-Up StudiesHumansMaleNeoplasm StagingPrognosisRectal NeoplasmsRetrospective StudiesRisk FactorsSurvival RateTime FactorsUnited Kingdom

Identifiers

PMID23287990
PMCPMC3593544
OpenAlexW2090361542

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.