ReviewIEEE transactions on ultrasonics, ferroelectrics, and frequency control2013
Nanoparticle delivery enhancement with acoustically activated microbubbles.
Review in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- A vortex-based hydrodynamic cavitation manufacturing platform to generate albumin microbubbles for delivery of chemotherapies to cancerous tumours.Ultrasonics sonochemistry · 2025Article
- Ultrasound enhanced siRNA delivery using cationic liposome-microbubble complexes for the treatment of squamous cell carcinoma.Nanotheranostics · 2024Article
- Insights on the Dynamic Innovative Tumor Targeted-Nanoparticles-Based Drug Delivery Systems Activation Techniques.International journal of nanomedicine · 2022Review
- Focused Ultrasound for Immunomodulation of the Tumor Microenvironment.Journal of immunology (Baltimore, Md. : 1950) · 2020Review
- Nanoparticle Activation Methods in Cancer Treatment.Biomolecules · 2019Review
- Recent Advances in the Use of Focused Ultrasound for Magnetic Resonance Image-Guided Therapeutic Nanoparticle Delivery to the Central Nervous System.Frontiers in pharmacology · 2019Review
- Cavitation Induced by Janus-Like Mesoporous Silicon Nanoparticles Enhances Ultrasound Hyperthermia.Frontiers in chemistry · 2019Article
- Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2018Article
- Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2015Article
- Vaporization dynamics of volatile perfluorocarbon droplets: a theoretical model and in vitro validation.Medical physics · 2014Article
- Volumetric contrast-enhanced ultrasound imaging of renal perfusion.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2014Article
- Improving the performance of phase-change perfluorocarbon droplets for medical ultrasonography: current progress, challenges, and prospects.Scientifica · 2014Review
- Nano/microparticles and ultrasound contrast agents.World journal of radiology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The application of microbubbles and ultrasound to deliver nanoparticle carriers for drug and gene delivery is an area that has expanded greatly in recent years. Under ultrasound exposure, microbubbles can enhance nanoparticle delivery by increasing cellular and vascular permeability. In this review, the underlying mechanisms of enhanced nanoparticle delivery with ultrasound and microbubbles and various proposed delivery techniques are discussed. Additionally, types of nanoparticles currently being investigated in preclinical studies, as well as the general limitations and benefits of a microbubble- based approach to nanoparticle delivery, are reviewed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.