Evidence map›Paper›PMID 23287625›Full record

ArticleBlood2013

Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia.

Scott J Hebbring, Susan L Slager, Narendranath Epperla, Joseph J Mazza, Zhan Ye, Zhiyi Zhou, Sara J Achenbach, Daniel A Vasco, Timothy G Call, Kari G Rabe and 9 more

Registry-linked trialOpen access · bronzeAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00626496 (Genetic Epidemiology of Lymphoproliferative Disorders), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00626496 recruitingnot on this map

Genetic Epidemiology of Lymphoproliferative Disorders

TypeobservationalSponsorMayo ClinicRan2004 to 2029Enrolled3,000ConditionsLymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Monoclonal B-Cell Lymphocytosis
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. PTPN22: the archetypal non-HLA autoimmunity gene.Nature reviews. Rheumatology · 2014
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Scott J Hebbring
Susan L Slager
Narendranath Epperla
Joseph J Mazza
Zhan Ye
Zhiyi Zhou
Sara J Achenbach
Daniel A Vasco
Timothy G Call
Kari G Rabe
Neil E Kay
Neil E Caporaso
Mark C Lanasa
Nicola J Camp
Sara S Strom
Lynn R Goldin
James R Cerhan
Murray H Brilliant
Steven J Schrodi
Marshfield Clinic · USMayo Clinic · USCenter for Human Genetics · USDivision of Cancer Epidemiology and GeneticsDuke Medical Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of Utah · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Research Training for Computation and Informatics in Biology and MedicineT15LM007359 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI Mark W. Craven, Colin Noel Dewey · 2002 to 2026
$22.6M
Genetic Epidemiology of Chronic Lymphocytic LeukemiaU01CA118444 · NCI · MAYO CLINIC ROCHESTER · PI SLAGER, SUSAN L · 2006 to 2015
$7.1M
Molecular Epidemiology of NHL and CLLR01CA092153 · NCI · MAYO CLINIC ROCHESTER · PI CERHAN, JAMES R · 2003 to 2012
$6.7M
Genome-Wide Study of Cataract and Low HDL in the Personalized Medicine Research PU01HG004608 · NHGRI · MARSHFIELD CLINIC RESEARCH FOUNDATION · PI MCCARTY, CATHERINE ANNE · 2007 to 2010
$3.3M
Molecular Pathogenesis of Monoclonal B Cell Lymphocytosis and CLLK08CA134919 · NCI · DUKE UNIVERSITY · PI LANASA, MARK C · 2011 to 2013
$483k
Intramural NIH HHSNCATS NIH HHS UL1 TR000427NCI NIH HHS CA118444NCI NIH HHS CA92153NCI NIH HHS K08 CA134919NCI NIH HHS N01-PC-35-1410NCRR NIH HHS UL1 RR025011NHGRI NIH HHS U01 HG004608NLM NIH HHS T15 LM007359
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansLeukemia, Lymphocytic, Chronic, B-CellOncogene Protein v-aktProtein Tyrosine Phosphatase, Non-Receptor Type 22Oncogene Protein v-aktProtein Tyrosine Phosphatase, Non-Receptor Type 22

Identifiers

PMID23287625
PMCPMC5091216
OpenAlexW2056010083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.