Evidence map›Paper›PMID 23287393›Full record

ReviewCell adhesion & migration

The myotomal basement membrane: insight into laminin-111 function and its control by Sonic hedgehog signaling.

Anne-Gaëlle Borycki

Abstract readReview
In one paragraph

Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
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  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anne-Gaëlle BoryckiDepartment of Biomedical Science, University of Sheffield, Sheffield, UK. a.g.borycki@sheffield.ac.uk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of laminin-containing basement membranes (BM) for adult muscle function is well established, in particular due to the severe phenotype of congenital muscular dystrophies in patients with mutations disrupting the BM-muscle cell interaction. Developing muscles in the embryo are also dependent on an intact BM. However, the processes controlled by BM-muscle cell interactions in the embryo are only beginning to be elucidated. In this review, we focus on the myotomal BM to illustrate the critical role of laminin-111 in BM assembly and function at the surface of embryonic muscle cells. The myotomal BM provides also an interesting paradigm to study the complex interplay between laminins-containing BM and growth factor-mediated signaling and activity.

Indexed as

Signal TransductionAnimalsBasement MembraneDNA-Binding ProteinsDystroglycansEmbryo, MammalianExtracellular MatrixHedgehog ProteinsLamininMiceMuscle, SkeletalMyogenic Regulatory Factor 5Protein TransportSomitesTranscription FactorsTranscription, GeneticDmrt2 protein, mouseDNA-Binding ProteinsDystroglycansHedgehog ProteinsLamininlaminin AMyf5 protein, mouseMyogenic Regulatory Factor 5Shh protein, mouseTranscription Factors

Identifiers

PMID23287393
PMCPMC3544789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.