ArticlePLoS neglected tropical diseases2012
Calodium hepaticum: household clustering transmission and the finding of a source of human spurious infection in a community of the Amazon region.
Article in PLoS neglected tropical diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Unveiling the hidden threats: a review of pathogen diversity and public health risks from bats, rodents, and non-human primates in Zambia (1990-2022).Frontiers in public health · 2024Pooled it
- Spurious passage ofJournal of clinical microbiology · 2026Article
- Prevalence of zoonotic nematodeParasitology · 2026Article
- Review
- Human parasitic infections of the class Adenophorea: global epidemiology, pathogenesis, prevention and control.Infectious diseases of poverty · 2024Review
- Wildlife as Food and Medicine in Brazil: A Neglected Zoonotic Risk?Pathogens (Basel, Switzerland) · 2024Review
- Micromammals as a reservoir for the zoonotic nematodeCurrent research in parasitology & vector-borne diseases · 2024Article
- Spurious infection by Calodium hepaticum (Bancroft, 1983) Moravec, 1982 and intestinal parasites in forest reserve dwellers in Western Brazilian Amazon.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
- Distribution and diversity of mosquitoes and Oropouche-like virus infection rates in an Amazonian rural settlement.PloS one · 2021Article
- An Ethnographic Approach to Characterizing Potential Pathways of Zoonotic Disease Transmission from Wild Meat in Guyana.EcoHealth · 2020Article
- First morphological and molecular analysis of Eucoleus boehmi like eggs in dogs from Argentina.Parasitology research · 2018Article
- OCCURRENCE OF Calodium hepaticum (BANCROFT, 1893) MORAVEC, 1982 EGGS IN FECES OF DOGS AND CATS IN LAGES, SANTA CATARINA, BRAZIL.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016Article
- High occurrence of Calodium hepaticum (syn. Capillaria hepatica) spurious infection in a village in the Atlantic Forest of southern Brazil.Memorias do Instituto Oswaldo Cruz · 2014Article
- An overview of the host spectrum and distribution of Calodium hepaticum (syn. Capillaria hepatica): part 2-Mammalia (excluding Muroidea).Parasitology research · 2014Review
- Dogs, cats, parasites, and humans in Brazil: opening the black box.Parasites & vectors · 2014Review
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCalodium hepaticum (syn. Capillaria hepatica) is a worldwide helminth parasite of which several aspects of transmission still remain unclear. In the Amazon region, the mechanism of transmission based on the ingestion of eggs present in the liver of wild mammals has been suggested as the cause of the spurious infections described. We performed an epidemiological investigation to determine the incidence, risk of spurious infection and the dynamics of transmission of C. hepaticum in a community of the Brazilian Amazon. METHODOLOGY/PRINCIPAL
findingsStool samples of 135 individuals, two dog feces and liver tissue from a peccary (captured and eaten by the residents) were analyzed by conventional microscopy. Dog feces were collected from the gardens of households presenting human cases of spurious C. hepaticum infections. Community practices and feeding habits related to the transmission of the parasite were investigated. The individual incidence of spurious infection was 6.7% (95% CI: 2.08-11.24). Cases of spurious infection were observed in 7.5% of the families and the household incidence was from 50% to 83.3%. The risk of spurious infection was 10-fold greater in persons consuming the liver of wild mammals (p = 0.02). The liver tissue of a peccary and one feces sample of a dog presented eggs of C. hepaticum. The consumption of the infected liver was the cause of the spurious infections reported in one household. CONCLUSIONS/SIGNIFICANCE: This is the first identification of a source of spurious infection by C. hepaticum in humans and we describe a high rate of incidence in household clusters related to game liver alimentary habits. The finding of a dog feces contaminating peridomiciliary ground suggests the risk of new infections. We conclude that the mechanism of transmission based on the ingestion of liver is important for the dynamics of transmission of C. hepaticum in the studied area.
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