ArticlePloS one2012
SOLiD-SAGE of endophyte-infected red fescue reveals numerous effects on host transcriptome and an abundance of highly expressed fungal secreted proteins.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 91 citations in OpenAlex.
- EgSPE, a secreted protein from Epichloë gansuensis, modulates symbiotic establishment and host drought tolerance.BMC plant biology · 2026Article
- Incorporating omics-based tools into endophytic fungal research.Biotechnology notes (Amsterdam, Netherlands) · 2024Review
- In-depth comparative transcriptome analysis of Purpureocillium sp. CB1 under cadmium stress.Applied microbiology and biotechnology · 2023Article
- TheMicroorganisms · 2023Article
- Comparative Transcriptomics Profiling of Perennial Ryegrass Infected with Wild Type or a ΔJournal of fungi (Basel, Switzerland) · 2023Article
- Transcriptomic Analyses Reveals Molecular Regulation of Photosynthesis byJournal of fungi (Basel, Switzerland) · 2022Article
- TheJournal of fungi (Basel, Switzerland) · 2022Article
- Microbiota manipulation through the secretion of effector proteins is fundamental to the wealth of lifestyles in the fungal kingdom.FEMS microbiology reviews · 2022Review
- Exploring fungal RiPPs from the perspective of chemical ecology.Fungal biology and biotechnology · 2022Review
- Vertically TransmittedJournal of fungi (Basel, Switzerland) · 2022Article
- Elucidating the Molecular Mechanisms by which Seed-Borne Endophytic Fungi,International journal of molecular sciences · 2021Article
- Exploring the Symbiotic Mechanism of a Virus-Mediated Endophytic Fungus in Its Host by Dual Unique Molecular Identifier-RNA Sequencing.mSystems · 2021Article
- Interaction between Grasses andMicroorganisms · 2021Review
- Antagonism to Plant Pathogens byPlants (Basel, Switzerland) · 2021Review
- Global Changes in AsexualMicroorganisms · 2021Article
- TheMicroorganisms · 2021Article
- Transcriptomic and Metabolomic Approaches Deepen Our Knowledge of Plant-Endophyte Interactions.Frontiers in plant science · 2021Review
- Review
- Lolium perenne apoplast metabolomics for identification of novel metabolites produced by the symbiotic fungus Epichloë festucae.The New phytologist · 2020Article
- Molecular mechanisms in grass-Epichloë interactions: towards endophyte driven farming to improve plant fitness and immunity.World journal of microbiology & biotechnology · 2020Review
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2 authors at 1 institution in 1 country.
Funding
Abstract
One of the most important plant-fungal symbiotic relationships is that of cool season grasses with endophytic fungi of the genera Epichloë and Neotyphodium. These associations often confer benefits, such as resistance to herbivores and improved drought tolerance, to the hosts. One benefit that appears to be unique to fine fescue grasses is disease resistance. As a first step towards understanding the basis of the endophyte-mediated disease resistance in Festuca rubra we carried out a SOLiD-SAGE quantitative transcriptome comparison of endophyte-free and Epichloë festucae-infected F. rubra. Over 200 plant genes involved in a wide variety of physiological processes were statistically significantly differentially expressed between the two samples. Many of the endophyte expressed genes were surprisingly abundant, with the most abundant fungal tag representing over 10% of the fungal mapped tags. Many of the abundant fungal tags were for secreted proteins. The second most abundantly expressed fungal gene was for a secreted antifungal protein and is of particular interest regarding the endophyte-mediated disease resistance. Similar genes in Penicillium and Aspergillus spp. have been demonstrated to have antifungal activity. Of the 10 epichloae whole genome sequences available, only one isolate of E. festucae and Neotyphodium gansuense var inebrians have an antifungal protein gene. The uniqueness of this gene in E. festucae from F. rubra, its transcript abundance, and the secreted nature of the protein, all suggest it may be involved in the disease resistance conferred to the host, which is a unique feature of the fine fescue-endophyte symbiosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.