ArticlePloS one2012
Multiple origins of kdr-type resistance in the house fly, Musca domestica.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Frequency of pyrethroid resistance in human head louse treatment: systematic review and meta-analysis.Parasite (Paris, France) · 2021Pooled it
- Insecticide resistance level and geographical distribution of target-site mutations in field collections of the house fly (Musca domestica) from Türkiye.Ecotoxicology (London, England) · 2026Article
- Distribution and frequency of genetic mutations in three insecticide targets in field populations ofFrontiers in cellular and infection microbiology · 2025Article
- Organochlorine knockdown-resistance (kdr) association in housefly (Parasite epidemiology and control · 2023Review
- Evaluation of resistance of human head lice to pyrethroid insecticides: A meta-analysis study.Heliyon · 2023Article
- Article
- Global Pattern ofCurrent tropical medicine reports · 2023Review
- Identification and phylogenetic analysis of voltage-gated sodium channel haplotypes in the malaria vector Anopheles sinensis using a high-throughput amplicon sequencing approach.Parasites & vectors · 2021Article
- A survey of insecticide resistance-conferring mutations in multiple targets in Anopheles sinensis populations across Sichuan, China.Parasites & vectors · 2021Article
- Impact of deltamethrin selection on kdr mutations and insecticide detoxifying enzymes in Aedes aegypti from Mexico.Parasites & vectors · 2020Article
- Evidence for both sequential mutations and recombination in the evolution of kdr alleles in Aedes aegypti.PLoS neglected tropical diseases · 2020Article
- Evolution of kdr haplotypes in worldwide populations of Aedes aegypti: Independent origins of the F1534C kdr mutation.PLoS neglected tropical diseases · 2020Article
- Article
- First detection of the kdr mutation (L1014F) in the plague vector Xenopsylla cheopis (Siphonaptera: Pulicidae).Parasites & vectors · 2019Article
- Target-site mutations (AChE-G119S and kdr) in Guangxi Anopheles sinensis populations along the China-Vietnam border.Parasites & vectors · 2019Article
- Levels of Resistance to Pyrethroid among DistinctBioMed research international · 2018Article
- Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera.PloS one · 2018Article
- Diversity and frequency of kdr mutations within Anopheles sinensis populations from Guangxi, China.Malaria journal · 2016Article
- Landscape genetic structure and evolutionary genetics of insecticide resistance gene mutations in Anopheles sinensis.Parasites & vectors · 2016Article
- L1014F-kdr Mutation in Indian Anopheles subpictus (Diptera: Culicidae) Arising From Two Alternative Transversions in the Voltage-Gated Sodium Channel and a Single PIRA-PCR for Their Detection.Journal of medical entomology · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insecticide resistance is a model phenotype that can be used to investigate evolutionary processes underlying the spread of alleles across a global landscape, while offering valuable insights into solving the problems that resistant pests present to human health and agriculture. Pyrethroids are one of the most widely used classes of insecticides world-wide and they exert their toxic effects through interactions with the voltage-sensitive sodium channel (Vssc). Specific mutations in Vssc (kdr, kdr-his and super-kdr) are known to cause resistance to pyrethroid insecticides in house flies. In order to determine the number of evolutionary origins of kdr, kdr-his and super-kdr, we sequenced a region of Vssc from house flies collected in the USA, Turkey and China. Our phylogenetic analysis of Vssc unequivocally supports the hypothesis of multiple independent origins of kdr, super-kdr and kdr-his on an unprecedented geographic scale. The implications of these evolutionary processes on pest management are discussed.
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