ArticlePloS one2012
The Neuronal Calcium Sensor protein Acrocalcin: a potential target of calmodulin regulation during development in the coral Acropora millepora.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Bacterial regulation of coral larval metamorphosis and settlement in Pocillopora damicornis.Communications biology · 2025Article
- Direct observation and quantitative characterization of chemotactic behaviors in Caribbean coral larvae exposed to organic and inorganic settlement cues.Scientific reports · 2025Article
- Calcium homeostasis disruption initiates rapid growth after micro-fragmentation in the scleractinian coralEcology and evolution · 2022Article
- Comparative Analysis of the Soluble Proteome and the Cytolytic Activity of Unbleached and BleachedMarine drugs · 2019Article
- Article
- The Complex Conformational Dynamics of Neuronal Calcium Sensor-1: A Single Molecule Perspective.Frontiers in molecular neuroscience · 2018Review
- Human Neuronal Calcium Sensor-1 Protein Avoids Histidine Residues To Decrease pH Sensitivity.The journal of physical chemistry. B · 2017Article
- Proteomic analysis of bleached and unbleached Acropora palmata, a threatened coral species of the Caribbean.Marine pollution bulletin · 2016Article
- Temperature-Dependent Conformational Properties of Human Neuronal Calcium Sensor-1 Protein Revealed by All-Atom Simulations.The journal of physical chemistry. B · 2016Article
- Developmental Progression in the Coral Acropora digitifera Is Controlled by Differential Expression of Distinct Regulatory Gene Networks.Genome biology and evolution · 2016Article
- Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
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Authors and funding
3 authors.
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Abstract
To understand the calcium-mediated signalling pathways underlying settlement and metamorphosis in the Scleractinian coral Acropora millepora, a predicted protein set derived from larval cDNAs was scanned for the presence of EF-hand domains (Pfam Id: PF00036). This approach led to the identification of a canonical calmodulin (AmCaM) protein and an uncharacterised member of the Neuronal Calcium Sensor (NCS) family of proteins known here as Acrocalcin (AmAC). While AmCaM transcripts were present throughout development, AmAC transcripts were not detected prior to gastrulation, after which relatively constant mRNA levels were detected until metamorphosis and settlement. The AmAC protein contains an internal CaM-binding site and was shown to interact in vitro with AmCaM. These results are consistent with the idea that AmAC is a target of AmCaM in vivo, suggesting that this interaction may regulate calcium-dependent processes during the development of Acropora millepora.
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