ArticleApplied physics letters2012
Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits.
Article in Applied physics letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- Capacitive coupling synchronizes autonomous microfluidic oscillators.Electrophoresis · 2018Article
- Multiple independent autonomous hydraulic oscillators driven by a common gravity head.Nature communications · 2015Article
- Microfluidic oscillators with widely tunable periods.Lab on a chip · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
This paper reveals a critical limitation in the electro-hydraulic analogy between a microfluidic membrane-valve (μMV) and an electronic transistor. Unlike typical transistors that have similar on and off threshold voltages, in hydraulic μMVs, the threshold pressures for opening and closing are significantly different and can change, even for the same μMVs depending on overall circuit design and operation conditions. We explain, in particular, how the negative values of the closing threshold pressures significantly constrain operation of even simple hydraulic μMV circuits such as autonomously switching two-valve microfluidic oscillators. These understandings have significant implications in designing self-regulated microfluidic devices.
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Registered trials
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