ArticleJournal of virology2013
The receptor-binding site of the measles virus hemagglutinin protein itself constitutes a conserved neutralizing epitope.
Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- Human neutralizing antibodies targeting the measles virus hemagglutinin and fusion surface proteins.Cell host & microbe · 2026Article
- Article
- What's going on with measles?Journal of virology · 2024Review
- Unveiling the affinity-stability relationship in anti-measles virus antibodies: a computational approach for hotspots prediction.Frontiers in molecular biosciences · 2023Article
- Formulation for the Targeted Delivery of a Vaccine Strain of Oncolytic Measles Virus (OMV) in Hyaluronic Acid Coated Thiolated Chitosan as a Green Nanoformulation for the Treatment of Prostate Cancer: A Viro-Immunotherapeutic Approach.International journal of nanomedicine · 2023Article
- Article
- Updates on Measles Incidence and Eradication: Emphasis on the Immunological Aspects of Measles Infection.Medicina (Kaunas, Lithuania) · 2022Review
- Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins.Cell reports. Medicine · 2021Article
- Molecular Epidemiology of B3 and D8 Measles Viruses through Hemagglutinin Phylogenetic History.International journal of molecular sciences · 2020Article
- Measles Encephalitis: Towards New Therapeutics.Viruses · 2019Review
- Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential.Journal of virology · 2018Article
- Cell-to-Cell Measles Virus Spread between Human Neurons Is Dependent on Hemagglutinin and Hyperfusogenic Fusion Protein.Journal of virology · 2018Article
- Perspective on Global Measles Epidemiology and Control and the Role of Novel Vaccination Strategies.Viruses · 2017Review
- Enhanced immunosurveillance for animal morbilliviruses using vesicular stomatitis virus (VSV) pseudotypes.Vaccine · 2016Article
- Review
- Eradication of measles: remaining challenges.Medical microbiology and immunology · 2016Review
- Review
- Article
- Article
- Molecular evolution of haemagglutinin (H) gene in measles virus.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Here, we provide direct evidence that the receptor-binding site of measles virus (MV) hemagglutinin protein itself forms an effective conserved neutralizing epitope (CNE). Several receptor-interacting residues constitute the CNE. Thus, viral escape from neutralization has to be associated with loss of receptor-binding activity. Since interactions with both the signaling lymphocyte activation molecule (SLAM) and nectin4 are critical for MV pathogenesis, its escape, which results from loss of receptor-binding activity, should not occur in nature.
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Registered trials
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