ReviewExtremophiles : life under extreme conditions2013
Multifunctional enzymes in archaea: promiscuity and moonlight.
Review in Extremophiles : life under extreme conditions, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Metals and Extremophilic Bacteria in Mining Environments: A Systematic Review.Microorganisms · 2026Review
- Molecular Identification and Bioinformatics Analysis ofPathogens (Basel, Switzerland) · 2024Article
- Moonlighting enzymes: when cellular context defines specificity.Cellular and molecular life sciences : CMLS · 2023Review
- Moonlight functions of glycolytic enzymes in cancer.Frontiers in molecular biosciences · 2023Review
- Medical implications of protein moonlighting.The Indian journal of medical research · 2019Article
- A High-Throughput Mass-Spectrometry-Based Assay for Identifying the Biochemical Functions of Putative Glycosidases.Chembiochem : a European journal of chemical biology · 2017Article
- Tracing the Repertoire of Promiscuous Enzymes along the Metabolic Pathways in Archaeal Organisms.Life (Basel, Switzerland) · 2017Article
- Insight into the Recent Genome Duplication of the Halophilic YeastG3 (Bethesda, Md.) · 2017Article
- Computational Analysis of Host-Pathogen Protein Interactions between Humans and Different Strains of EnterohemorrhagicFrontiers in cellular and infection microbiology · 2017Article
- High-throughput recombinant protein expression in Escherichia coli: current status and future perspectives.Open biology · 2016Review
- The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules.Microbial cell factories · 2015Article
- Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii.Journal of bacteriology · 2015Article
- Article
- Genetically modified proteins: functional improvement and chimeragenesis.Bioengineered · 2015Review
- β-alanine biosynthesis in Methanocaldococcus jannaschii.Journal of bacteriology · 2014Article
- Profiling the orphan enzymes.Biology direct · 2014Review
- Enzyme recruitment and its role in metabolic expansion.Biochemistry · 2014Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enzymes from many archaea colonizing extreme environments are of great interest because of their potential for various biotechnological processes and scientific value of evolution. Many enzymes from archaea have been reported to catalyze promiscuous reactions or moonlight in different functions. Here, we summarize known archaeal enzymes of both groups that include different kinds of proteins. Knowledge of their biochemical properties and three-dimensional structures has proved invaluable in understanding mechanism, application, and evolutionary implications of this manifestation. In addition, the review also summarizes the methods to unravel the extra function which almost was discovered serendipitously. The study of these amazing enzymes will provide clues to optimize protein engineering applications and how enzymes might have evolved on Earth.
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