ArticleThe ISME journal2013
Marine microbial symbiosis heats up: the phylogenetic and functional response of a sponge holobiont to thermal stress.
Article in The ISME journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 285 citations in OpenAlex.
- Induced Dysbiosis Modifies Physiological Responses to Warming in a Temperate Sponge.Environmental microbiology · 2026Article
- Cryptic Interactions in a Marine Microcosm: Sponges Shape the Microbiome of a Resident Goby.Molecular ecology · 2026Article
- Low-Dose HGlobal challenges (Hoboken, NJ) · 2026Article
- The chromosomal genome sequence of the sponge,Wellcome open research · 2026Article
- Microbial communities associated with two populations of the spongeBiodiversity data journal · 2026Article
- Article
- Too hot for my bugs: mediterranean heatwave disrupts associated microbiomes in the sponge Petrosia ficiformis.Environmental microbiome · 2025Article
- Safeguarding microbial biodiversity: microbial conservation specialist group within the species survival commission of the International Union for Conservation of Nature.FEMS microbiology ecology · 2025Article
- Disruption of host-associated and benthic microbiota affects reproductive output and settlement of a habitat-forming macroalga.Proceedings. Biological sciences · 2025Article
- Safeguarding microbial biodiversity: microbial conservation specialist group within the species survival commission of the International Union for Conservation of Nature.The ISME journal · 2025Article
- Ecological and evolutionary responses of earthworm holobionts to environmental changes.The ISME journal · 2025Review
- Safeguarding microbial biodiversity: microbial conservation specialist group within the species survival commission of the International Union for Conservation of Nature.Sustainable microbiology · 2025Article
- Influence of Temperature and Saline Conditions on Bacteria Naturally Associated With the Cnidarian HostInternational journal of microbiology · 2025Article
- Selective shaping of prokaryotic communities and core symbiont maintenance suggest large-scale aquarium facilities as reservoirs of microbiome diversity in octocorals.Frontiers in microbiology · 2025Article
- Article
- Development and validation of an experimental life support system to study coral reef microbial communities.Scientific reports · 2024Article
- Diversity, composition and potential roles of sedimentary microbial communities in different coastal substrates around subtropical Okinawa Island, Japan.Environmental microbiome · 2024Article
- Vanadium Accumulation and Reduction by Vanadium-Accumulating Bacteria Isolated from the Intestinal Contents of Ciona robusta.Marine biotechnology (New York, N.Y.) · 2024Article
- Microbiome changes through the ontogeny of the marine sponge Crambe crambe.Environmental microbiome · 2024Article
- Impacts of humic substances, elevated temperature, and UVB radiation on bacterial communities of the marine sponge Chondrilla sp.FEMS microbiology ecology · 2024Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large-scale mortality of marine invertebrates is a major global concern for ocean ecosystems and many sessile, reef-building animals, such as sponges and corals, are experiencing significant declines through temperature-induced disease and bleaching. The health and survival of marine invertebrates is often dependent on intimate symbiotic associations with complex microbial communities, yet we have a very limited understanding of the detailed biology and ecology of both the host and the symbiont community in response to environmental stressors, such as elevated seawater temperatures. Here, we use the ecologically important sponge Rhopaloeides odorabile as a model to explore the changes in symbiosis during the development of temperature-induced necrosis. Expression profiling of the sponge host was examined in conjunction with the phylogenetic and functional structure and the expression profile of the symbiont community. Elevated temperature causes an immediate stress response in both the host and symbiont community, including reduced expression of functions that mediate their partnership. Disruption to nutritional interdependence and molecular interactions during early heat stress further destabilizes the holobiont, ultimately leading to the loss of archetypal sponge symbionts and the introduction of new microorganisms that have functional and expression profiles consistent with a scavenging lifestyle, a lack virulence functions and a high growth rate. Previous models have postulated various mechanisms of mortality and disease in marine invertebrates. Our study suggests that interruption of symbiotic interactions is a major determinant for mortality in marine sessile invertebrates. High symbiont specialization and low functional redundancy, thus make these holobionts extremely vulnerable to environmental perturbations, including climate change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.