ArticleThe World Allergy Organization journal2008
Epinephrine: the drug of choice for anaphylaxis-a statement of the world allergy organization.
Article in The World Allergy Organization journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Synthesis of NiO nanostructures as electrode materials for the voltammetric determination of epinephrine in the presence of acetaminophen.ADMET & DMPK · 2026Article
- Reframing ATR: from the immunologic/nonimmunologic dichotomy to adaptive, innate, and physicochemical drivers within the allergy-inflammation-coagulation axis.Frontiers in immunology · 2026Review
- Epinephrine-induced lactic acidosis during the management of anaphylactic shock: a case report.Clinical and experimental emergency medicine · 2025Article
- IgE and non-IgE-mediated pathways in anaphylaxis.Seminars in immunopathology · 2025Review
- Emergency Monitoring Following A Diagnosis of Anaphylaxis.Current allergy and asthma reports · 2025Review
- Parental knowledge and attitudes toward food allergies: a cross-sectional study on determinants and educational needs.BMC public health · 2024Article
- Design and Optimization of Molecularly Imprinted Polymer Targeting Epinephrine Molecule: A Theoretical Approach.Polymers · 2024Article
- Food Allergy Reaction Severity and Management in a Diverse Population.The journal of allergy and clinical immunology. In practice · 2024Article
- Bed Bugs (Hemiptera, Cimicidae): A Global Challenge for Public Health and Control Management.Diagnostics (Basel, Switzerland) · 2023Review
- Article
- Review
- Investigation of the underuse of adrenaline (epinephrine) and prognosis among patients with anaphylaxis at emergency department admission.Frontiers in medicine · 2023Article
- High-speed wide-field photoacoustic microscopy using a cylindrically focused transparent high-frequency ultrasound transducer.Photoacoustics · 2022Article
- The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis.Journal of clinical medicine · 2022Article
- An unusual presentation of anaphylaxis with severe hypertension: a case report.Journal of medical case reports · 2022Article
- Potential prophylactic efficacy of mast cell stabilizers against COVID-19 vaccine-induced anaphylaxis.Clinical and molecular allergy : CMA · 2021Article
- High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner.Photoacoustics · 2021Article
- Severe anaphylaxis caused by intravenous anti-cancer drugs.Cancer medicine · 2021Article
- Updated anaphylaxis guidelines: management in infants and children.Australian prescriber · 2021Review
- Fatal anaphylaxis to intravenous ondansetron: A case report.Clinical case reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anaphylaxis is an acute and potentially lethal multisystem allergic reaction. Most consensus guidelines for the past 30 years have held that epinephrine is the drug of choice and the first drug that should be administered in acute anaphylaxis. Some state that properly administered epinephrine has no absolute contraindication in this clinical setting. A committee of anaphylaxis experts assembled by the World Allergy Organization has examined the evidence from the medical literature concerning the appropriate use of epinephrine for anaphylaxis. The committee strongly believes that epinephrine is currently underused and often dosed suboptimally to treat anaphylaxis, is underprescribed for potential future self-administration, that most of the reasons proposed to withhold its clinical use are flawed, and that the therapeutic benefits of epinephrine exceed the risk when given in appropriate intramuscular doses.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.