ArticleJournal of clinical hypertension (Greenwich, Conn.)2013
Serum uric acid, inflammation, and nondipping circadian pattern in essential hypertension.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Efficacy of angiotensin receptor blockers for nocturnal blood pressure reduction: a systematic review and meta-analysis.Annals of medicine · 2024Pooled it
- Serum Uric Acid Changes in Relation to Nighttime Blood Pressure Dipping Status in Patients on Antihypertensive Therapy.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Dose-dependent effects of SGLT2 inhibitors on circadian blood pressure in hypertensive patients with diabetes: A systematic review and Bayesian network meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Systemic Immune-Inflammation Index and Unconjugated Bilirubin Levels Are Associated with Pseudoexfoliation Syndrome.Journal of ophthalmic & vision research · 2025Article
- Blood Pressure Patterns and Hepatosteatosis: Cardiometabolic Risk Assessment in Dipper and Non-Dipper Phenotypes.Journal of clinical medicine · 2024Article
- Establishment of a potent weighted risk model for determining the progression of diabetic kidney disease.Journal of translational medicine · 2023Article
- Factors Associating with Non-Dipping Pattern of Nocturnal Blood Pressure in Patients with Essential Hypertension.Journal of clinical medicine · 2023Article
- Fatty Acid Levels and Their Inflammatory Metabolites Are Associated with the Nondipping Status and Risk of Obstructive Sleep Apnea Syndrome in Stroke Patients.Biomedicines · 2022Article
- Direct Relationship Between Uric Acid and C-Reactive Protein and Its Implication in the Chronic Kidney Disease.Indian journal of clinical biochemistry : IJCB · 2022Article
- High Levels of Thromboxane (TX) Are Associated with the Sex-Dependent Non-Dipping Phenomenon in Ischemic Stroke Patients.Journal of clinical medicine · 2022Article
- Association Between Serum Uric Acid Levels and Traditional Cardiovascular Risk Factors in Xiamen Residents of China: A Real-World Study.Frontiers in cardiovascular medicine · 2022Article
- Clinical risk factors and predictive score for the non-dipper profile in hypertensive patients: a case-control study.Clinical hypertension · 2021Article
- Expanding role for single-pill combination drug therapy in the initial treatment of hypertension?Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Clinical effectiveness and safety of amlodipine/losartan-based single-pill combination therapy in patients with hypertension: Findings from real-world, multicenter observational databases.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Variation in serum urate levels in the absence of gout and urate lowering therapy.BMC rheumatology · 2021Article
- Association between Serum Uric Acid and Pre-hypertension and Hypertension among Chinese Adults.Arquivos brasileiros de cardiologia · 2021Article
- Article
- Uric Acid and Hypertension: An Update With Recommendations.American journal of hypertension · 2020Review
- The interaction between serum uric acid and triglycerides level on blood pressure in middle-aged and elderly individuals in China: result from a large national cohort study.BMC cardiovascular disorders · 2020Article
- Article
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11 authors at 4 institutions in 2 countries.
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Abstract
Uric acid (UA) is independently associated with the emergence of hypertension. Nocturnal nondipping pattern of hypertension is associated with a greater risk of cardiovascular, renal, and cerebrovascular complications than dippers. The aim of the present study was to evaluate the relationship between the circadian blood pressure rhythm and UA level in patients with newly diagnosed essential hypertension. The study included 112 essential hypertensive patients and 50 healthy controls. The hypertensive patients were divided into two groups according to the results of 24-hour ambulatory blood pressure monitoring, including 60 dippers (35 men, 25 women; mean age, 52.6±15.8 years) and 52 nondippers (29 men, 23 women; mean age, 55.9±13.2 years). Nondippers had significantly higher serum UA levels than the dippers and controls (5.8±0.8, 5.1±0.9 and 4.2±0.9 mg/dL, respectively; P<.001). Serum high-sensitivity C-reactive protein levels were also significantly higher in the nondipper group than the other groups (P<.001) and significantly correlated with serum UA (r=0.358, P<.001). Multivariate logistic regression analysis revealed an independent positive association between serum UA levels and nondipper pattern (odds ratio, 2.28; 95% confidence interval, 1.33-3.94; P=.003). Serum UA is strongly and independently associated with the nondipper circadian pattern in essential hypertension.
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