Evidence map›Paper›PMID 23281407›Full record

ReviewThe Journal of clinical investigation2013

Adaptive immunity in atherogenesis: new insights and therapeutic approaches.

Andrew H Lichtman, Christoph J Binder, Sotirios Tsimikas, Joseph L Witztum

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 199 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Progenitor exhausted PD-1Nature cardiovascular research · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Application of Photodynamic Therapy in Cardiology.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Immunity in Atherosclerosis: Focusing on T and B Cells.International journal of molecular sciences · 2021
    Review
  18. The changing landscape of atherosclerosis.Nature · 2021 · on this map
    Review
  19. Review
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Andrew H LichtmanVascular Research Division, Department of Pathology, Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA. alichtman@rics.bwh.harvard.edu
Christoph J Binder
Sotirios Tsimikas
Joseph L Witztum
University of California San Diego · USAustrian Academy of Sciences · ATBrigham and Women's Hospital · US

Funding

Regulation of T Cell Responses in AtherosclerosisR01HL087282 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LICHTMAN, ANDREW H · 2007 to 2015
$4.0M
NHLBI NIH HHS R01 HL087282
6 · The paper itself

Abstract

Many remarkable advances have improved our understanding of the cellular and molecular events in the pathogenesis of atherosclerosis. Chief among these is the accumulating knowledge of how the immune system contributes to all phases of atherogenesis, including well-known inflammatory reactions consequent to intimal trapping and oxidation of LDL. Advances in our understanding of the innate and adaptive responses to these events have helped to clarify the role of inflammation in atherogenesis and suggested new diagnostic modalities and novel therapeutic targets. Here we focus on recent advances in understanding how adaptive immunity affects atherogenesis.

Indexed as

Adaptive ImmunityAtherosclerosisAnimalsHumansInflammationLipoproteins, LDLOxidation-ReductionLipoproteins, LDL

Identifiers

PMID23281407
PMCPMC3533280
OpenAlexW2050957960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.