Evidence map›Paper›PMID 23280855›Full record

ArticleMagnetic resonance in medicine2013

Error model for reduction of cardiac and respiratory motion effects in quantitative liver DW-MRI.

Paul Murphy, Tanya Wolfson, Anthony Gamst, Claude Sirlin, Mark Bydder

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Usefulness of Adaptive Complex Signal Average Diffusion-weighted MR Imaging of the Abdomen.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Technical Advancements in Abdominal Diffusion-weighted Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Improving the Quality of Diffusion-weighted Imaging of the Left Hepatic Lobe Using Weighted Averaging of Signals from Multiple Excitations.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2019
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul MurphyDepartment of Radiology, University of California, San Diego, California.
Tanya Wolfson
Anthony Gamst
Claude Sirlin
Mark Bydder

Funding

Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
NCRR NIH HHS RR1225NIBIB NIH HHS T32 EB005970NIBIB NIH HHS T32EB005970
6 · The paper itself

Abstract

Diffusion-weighted images of the liver exhibit signal dropout from cardiac and respiratory motion, particularly in the left lobe. These artifacts cause bias and variance in derived parameters that quantify intravoxel incoherent motion. Many models of diffusion have been proposed, but few separate attenuation from diffusion or perfusion from that of bulk motion. The error model proposed here (Beta*LogNormal) is intended to accomplish that separation by modeling stochastic attenuation from bulk motion as multiplication by a Beta-distributed random variate. Maximum likelihood estimation with this error model can be used to derive intravoxel incoherent motion parameters separate from signal dropout, and does not require a priori specification of parameters to do so. Liver intravoxel incoherent motion parameters were derived for six healthy subjects under this error model and compared with least-squares estimates. Least-squares estimates exhibited bias due to cardiac and respiratory gating and due to location within the liver. Bias from these factors was significantly reduced under the Beta*LogNormal model, as was within-organ parameter variance. Similar effects were appreciable in diffusivity maps in two patients with focal liver lesions. These results suggest that, relative to least-squares estimation, the Beta*LogNormal model accomplishes the intended reduction of bias and variance from bulk motion in liver diffusion imaging.

Indexed as

ArtifactsModels, StatisticalAdultAgedAlgorithmsCardiac-Gated Imaging TechniquesComputer SimulationData Interpretation, StatisticalDiffusion Magnetic Resonance ImagingFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedLiver NeoplasmsMaleMiddle Agedabdominal/pelvicanatomylivernormal

Identifiers

PMID23280855
PMCPMC4142067

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.