Evidence map›Paper›PMID 23280357›Full record

ReviewPhysiology (Bethesda, Md.)2013

Chemosensors in the nose: guardians of the airways.

Marco Tizzano, Thomas E Finger

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. G protein subunit GeLife · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Detection of intrinsic cholinergic system in the human lacrimal drainage system: evidence and potential implications.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marco TizzanoDepartment of Cell & Developmental Biology, Rocky Mountain Taste & Smell Center, University of Colorado School of Medicine, Aurora, Colorado, USA.
Thomas E Finger

Funding

NIDCD P30 Core: Rocky Mountain Taste and Smell CenterP30DC004657 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI KINNAMON, SUE C., RESTREPO, DIEGO · 2000 to 2014
$7.6M
ULTRASTRUCTURAL CORRELATES OF DEVELOPMENT IN TASTE BUDSP01DC000244 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI JAFEK, BRUCE W · 1989 to 2002
$2.9M
Nasal Solitary Chemoreceptor Cells: Detection of Pathogenic BacteriaR01DC009820 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI FINGER, THOMAS E, KINNAMON, SUE C. · 2009 to 2013
$2.2M
Nasal solitary chemosensory cells linking irritation to inflammationR03DC012413 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI TIZZANO, MARCO · 2012 to 2014
$445k
NIDCD NIH HHS P01 DC000244NIDCD NIH HHS P30 DC004657NIDCD NIH HHS P30 DC-04657NIDCD NIH HHS R01 DC-009820NIDCD NIH HHS R01 DC009820NIDCD NIH HHS R03 DC-012413NIDCD NIH HHS R03 DC012413
6 · The paper itself

Abstract

The G-protein-coupled receptor molecules and downstream effectors that are used by taste buds to detect sweet, bitter, and savory tastes are also utilized by chemoresponsive cells of the airways to detect irritants. Here, we describe the different cell types in the airways that utilize taste-receptor signaling to trigger protective epithelial and neural responses to potentially dangerous toxins and bacterial infection.

Indexed as

AnimalsCell CommunicationChemoreceptor CellsHumansNoseReceptors, G-Protein-CoupledSignal TransductionTaste BudsReceptors, G-Protein-Coupled

Identifiers

PMID23280357
PMCPMC3736818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.