Evidence map›Paper›PMID 23279801›Full record

ReviewCurrent opinion in plant biology2013

Molecular mechanisms of robustness in plants.

Janne Lempe, Jennifer Lachowiec, Alessandra M Sullivan, Christine Queitsch

Abstract readReview
In one paragraph

Review in Current opinion in plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Genes for Yield Stability in Tomatoes.Advanced genetics (Hoboken, N.J.) · 2021
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Large-effect flowering time mutations reveal conditionally adaptive paths through fitness landscapes inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  16. Article
  17. Article
  18. Redundancy, Feedback, and Robustness in theFrontiers in genetics · 2018
    Article
  19. Article
  20. Bimodality of stable and plastic traits in plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Janne LempeDepartment of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, WA 98195, USA.
Jennifer Lachowiec
Alessandra M Sullivan
Christine Queitsch
University of Washington · US

Funding

INTERDISCIPLINARY TRAINING IN GENOMIC SCIENCEST32HG000035 · NHGRI · UNIVERSITY OF WASHINGTON · PI Bruce Colston Trapnell · 1995 to 2026
$24.2M
Does organismal robustness explain the missing heritability in complex diseases?DP2OD008371 · OD · UNIVERSITY OF WASHINGTON · PI QUEITSCH, CHRISTINE · 2011 to 2011
$2.3M
NHGRI NIH HHS T32 HG000035NHGRI NIH HHS T32 HG00035NIH HHS DP2 OD008371NIH HHS DP2OD008371
6 · The paper itself

Abstract

Robustness, the ability of organisms to buffer phenotypes against perturbations, has drawn renewed interest among developmental biologists and geneticists. A growing body of research supports an important role of robustness in the genotype to phenotype translation, with far-reaching implications for evolutionary processes and disease susceptibility. Similar to animals and fungi, plant robustness is a function of genetic network architecture. Most perturbations are buffered; however, perturbation of network hubs destabilizes many traits. Here, we review recent advances in identifying molecular robustness mechanisms in plants that have been enabled by a combination of classical genetics and population genetics with genome-scale data.

Indexed as

Gene Regulatory NetworksPlant DevelopmentArabidopsisEvolution, MolecularGenomicsGenotypeMeristemMutationPhenotypePlantsSeedlings

Identifiers

PMID23279801
PMCPMC3577948
OpenAlexW2005333735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.