ArticleMolecular ecology2013
Progressive genome-wide introgression in agricultural Campylobacter coli.
Article in Molecular ecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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Who cites it
92 citing papers in PubMed.
- Epistasis and co-adaptation in bacterial genome evolution.Nature reviews. Genetics · 2026Review
- Geographic clustering and population structures ofMicrobial genomics · 2026Article
- Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy.Nature communications · 2025Article
- Genomic epidemiology and the evolution ofMicrobial genomics · 2025Article
- Growth rates and metabolic traits differ by diarrhoeal manifestation inJournal of medical microbiology · 2025Article
- Strain sharing and mobile genetic elements shape the interconnected resistomes of Campylobacter coli in Brazil.BMC biology · 2025Article
- KPop: accurate and scalable comparative analysis of microbial genomes by sequence embeddings.Genome biology · 2025Article
- Characterization of aquatic clade 2 and 3 Campylobacter coli isolates from Slovenia reveals admixture with other Campylobacter species.BMC microbiology · 2025Article
- Sharing ofmBio · 2025Article
- Genomic diversity ofMicrobial genomics · 2024Article
- Machine learning to attribute the source of Campylobacter infections in the United States: A retrospective analysis of national surveillance data.The Journal of infection · 2024Article
- Graphite: painting genomes using a colored de Bruijn graph.NAR genomics and bioinformatics · 2024Article
- Article
- RecGraph: recombination-aware alignment of sequences to variation graphs.Bioinformatics (Oxford, England) · 2024Article
- Occurrence of Florfenicol and Linezolid Resistance and Emergence ofInternational journal of microbiology · 2024Article
- Application of TraDIS to define the core essential genome of Campylobacter jejuni and Campylobacter coli.BMC microbiology · 2023Article
- Roles of viable but non-culturable state in the survival ofFrontiers in cellular and infection microbiology · 2023Article
- Phylogenetic Analysis of Bacterial Pathogen Genomes.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Gene flow and introgression are pervasive forces shaping the evolution of bacterial species.Genome biology · 2022Article
- A scalable analytical approach from bacterial genomes to epidemiology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
32 more citing papers are in PubMed but not listed here.
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24 authors.
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Abstract
Hybridization between distantly related organisms can facilitate rapid adaptation to novel environments, but is potentially constrained by epistatic fitness interactions among cell components. The zoonotic pathogens Campylobacter coli and C. jejuni differ from each other by around 15% at the nucleotide level, corresponding to an average of nearly 40 amino acids per protein-coding gene. Using whole genome sequencing, we show that a single C. coli lineage, which has successfully colonized an agricultural niche, has been progressively accumulating C. jejuni DNA. Members of this lineage belong to two groups, the ST-828 and ST-1150 clonal complexes. The ST-1150 complex is less frequently isolated and has undergone a substantially greater amount of introgression leading to replacement of up to 23% of the C. coli core genome as well as import of novel DNA. By contrast, the more commonly isolated ST-828 complex bacteria have 10-11% introgressed DNA, and C. jejuni and nonagricultural C. coli lineages each have <2%. Thus, the C. coli that colonize agriculture, and consequently cause most human disease, have hybrid origin, but this cross-species exchange has so far not had a substantial impact on the gene pools of either C. jejuni or nonagricultural C. coli. These findings also indicate remarkable interchangeability of basic cellular machinery after a prolonged period of independent evolution.
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