Trial reportAlcoholism, clinical and experimental research2013
Neurophysiological correlates of moderate alcohol consumption in older and younger social drinkers.
Trial report in Alcoholism, clinical and experimental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Alcohol and Neural Dynamics: A Meta-analysis of Acute Alcohol Effects on Event-Related Brain Potentials.Biological psychiatry · 2021Pooled it
- Working Memory Performance Following Acute Alcohol: Replication and Extension of Dose by Age Interactions.Journal of studies on alcohol and drugs · 2019Trial
- Effects of Age and Acute Moderate Alcohol Administration on Neurophysiology During Simulated Driving.Alcoholism, clinical and experimental research · 2016Trial
- Neurophysiological correlates of moderate alcohol consumption in older and younger social drinkers.Alcoholism, clinical and experimental research · 2013Trial
- Linking alcohol use to Alzheimer's disease: Interactions with aging and APOE along immune pathways.Medical research archives · 2024Article
- Neural and Psychosocial Mechanisms Underlying Alcohol Use and Pain Interactions: Overview of Current Evidence and Future Directions.Current addiction reports · 2023Article
- Association of cerebellar and pre-motor cortex gray matter density with subjective intoxication and subjective response following acute alcohol intake.Scientific reports · 2023Article
- Acute Alcohol Intake Produces Widespread Decreases in Cortical Resting Signal Variability in Healthy Social Drinkers.Alcoholism, clinical and experimental research · 2020Article
- Effects of Age and Acute Moderate Alcohol Consumption on Electrophysiological Indices of Attention.Journal of studies on alcohol and drugs · 2020Article
- Acute alcohol intake alters resting state functional connectivity of nucleus accumbens with pain-related corticolimbic structures.Drug and alcohol dependence · 2020Article
- Alcohol's Unique Effects on Cognition in Women: A 2020 (Re)view to Envision Future Research and Treatment.Alcohol research : current reviews · 2020Review
- Cognitive training as a component of treatment of alcohol use disorder: A review.Neuropsychology · 2019Review
- Clarifying the neurobehavioral sequelae of moderate drinking lifestyles and acute alcohol effects with aging.International review of neurobiology · 2019Review
- Alcohol affects the P3 component of an adaptive stop signal task ERP.Alcohol (Fayetteville, N.Y.) · 2018Article
- Abnormal Resting-State Quantitative Electroencephalogram in Children With Central Auditory Processing Disorder: A Pilot Study.Frontiers in neuroscience · 2018Article
- Effects of Age and Acute Moderate Alcohol Administration on Electrophysiological Correlates of Working Memory Maintenance.Alcoholism, clinical and experimental research · 2016Article
- Disruption of sensory gating by moderate alcohol doses.Psychopharmacology · 2014Article
- Age-related effects of alcohol from adolescent, adult, and aged populations using human and animal models.Alcoholism, clinical and experimental research · 2014Review
- Acute effects of moderate alcohol on psychomotor, set shifting, and working memory function in older and younger social drinkers.Journal of studies on alcohol and drugs · 2014Article
- Interactions between age and moderate alcohol effects on simulated driving performance.Psychopharmacology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundNearly 40% of adults aged 65 and older in the United States consume alcohol. Research in older adults has largely examined potential health effects of a moderate drinking lifestyle. Examination of acute effects in this population is generally lacking. To investigate alcohol-induced alteration of electrophysiological correlates of attention in this population, we employed a covert attentional task. We hypothesized that moderate alcohol administration as well as older age would reduce P3 amplitude and increase latency. We anticipated an interaction such that, relative to their age-matched controls, older adults receiving alcohol would be more affected than their younger counterparts.
methodsParticipants included healthy older (aged 50 to 67; n = 20; 9 men) and younger (aged 25 to 35; n = 12; 5 men) moderate drinkers. Participants received either a moderate dose of alcohol (breath alcohol concentration ~50 mg/dl) or a placebo beverage. Following absorption, the task was administered and neurophysiological measures were obtained. P3 amplitude and latency were separately subjected to ANOVA across cue conditions using age and dose as independent variables.
resultsAs predicted, P3 amplitude in older adults was significantly lower than in younger adults across cue conditions. An age by alcohol interaction was detected, revealing that older adults receiving alcohol showed lower P3 amplitudes than any other group. An age effect for P3 latency was found, with older adults having longer latencies than their younger counterparts. A significant age by alcohol interaction for P3 latency was detected, revealing that older adults receiving alcohol displayed delayed P3 latencies relative to older adults receiving placebo. In contrast, younger adults receiving alcohol had reduced latency compared to those receiving placebo, although this effect did not reach significance.
conclusionsResults suggest that older adults demonstrated alcohol-related shifts in P3 characteristics during an intentional attention task, whereas younger adults failed to demonstrate this pattern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.