Evidence map›Paper›PMID 23276920›Full record

ReviewFrontiers in bioscience (Landmark edition)2013

The power of yeast to model diseases of the powerhouse of the cell.

Matthew G Baile, Steven M Claypool

Abstract readReview
In one paragraph

Review in Frontiers in bioscience (Landmark edition), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Genes · 2021
    Review
  5. Review
  6. Review
  7. Life science alliance · 2019
    Article
  8. Article
  9. Emerging Roles in the Biogenesis of CytochromeFrontiers in cell and developmental biology · 2019
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Power(2): the power of yeast genetics applied to the powerhouse of the cell.Trends in endocrinology and metabolism: TEM · 2015
    Review
  16. Article
  17. Review
  18. Review
  19. The yeast sphingolipid signaling landscape.Chemistry and physics of lipids · 2014
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew G BaileDept. of Physiology, Johns Hopkins School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205-2185, USA.
Steven M Claypool

Funding

BIOCHEMISTRY, CELLULAR AND MOLECULAR BIOLOGY PROGRAMT32GM007445 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 1985 to 2021
$24.1M
Characterizing tafazzin and Barth syndrome mutant tafazzinsR00HL089185 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CLAYPOOL, STEVEN MICHAEL · 2008 to 2010
$740k
NHLBI NIH HHS R00 HL089185NHLBI NIH HHS R00HL089185NIGMS NIH HHS T32 GM007445
6 · The paper itself

Abstract

Mitochondria participate in a variety of cellular functions. As such, mitochondrial diseases exhibit numerous clinical phenotypes. Because mitochondrial functions are highly conserved between humans and Saccharomyces cerevisiae, yeast are an excellent model to study mitochondrial disease, providing insight into both physiological and pathophysiological processes.

Indexed as

Models, BiologicalAdenosine TriphosphatasesCardiolipinsCarrier ProteinsDNA, MitochondrialDNA ReplicationElectron Transport Complex IIElectron Transport Complex IIIElectron Transport Complex IVHumansMembrane ProteinsMetalloendopeptidasesMitochondriaMitochondrial ADP, ATP TranslocasesMitochondrial DiseasesMitochondrial Membrane Transport ProteinsAdenosine TriphosphatasesCardiolipinsCarrier ProteinsDNA, MitochondrialElectron Transport Complex IIElectron Transport Complex IIIElectron Transport Complex IVMembrane ProteinsMetalloendopeptidasesMitochondrial ADP, ATP TranslocasesMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsMitochondrial ProteinsMitochondrial Proton-Translocating ATPasesoligomycin sensitivity-conferring proteinSaccharomyces cerevisiae ProteinsSuccinate DehydrogenaseSYM1 protein, S cerevisiaeTOM7 protein, S cerevisiaeYTA12 protein, S cerevisiae

Identifiers

PMID23276920
PMCPMC3874933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.