Trial reportPreventive medicine2013
PROSPER community-university partnership delivery system effects on substance misuse through 6 1/2 years past baseline from a cluster randomized controlled intervention trial.
Trial report in Preventive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Fadeout and persistence of intervention impacts on social-emotional and cognitive skills in children and adolescents: A meta-analytic review of randomized controlled trials.Psychological bulletin · 2024Pooled it
- Family-based prevention programmes for alcohol use in young people.The Cochrane database of systematic reviews · 2019Pooled it
- For Whom Do Parenting Interventions to Prevent Adolescent Substance Use Work?Prevention science : the official journal of the Society for Prevention Research · 2018Pooled it
- Effective Parenting Interventions to Reduce Youth Substance Use: A Systematic Review.Pediatrics · 2016Pooled it
- Universal school-based prevention for illicit drug use.The Cochrane database of systematic reviews · 2014Pooled it
- Applying the PROSPER prevention delivery system with middle schools: Emerging adulthood effects on substance misuse and conduct problem behaviors through 14 years past baseline.Child development · 2022Trial
- Developmental cascade effects of a parenting-focused program for divorced families on competence in emerging adulthood.Development and psychopathology · 2021Trial
- Adolescent Internalizing Symptoms and the "Tightknittedness" of Friendship Groups.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2020Trial
- Examining the Highs and Lows of the Collaborative Relationship Between Technical Assistance Providers and Prevention Implementers.Prevention science : the official journal of the Society for Prevention Research · 2018Trial
- A randomized, controlled trial of the family check-up model in public secondary schools: Examining links between parent engagement and substance use progressions from early adolescence to adulthood.Journal of consulting and clinical psychology · 2016Trial
- Effects of Communities That Care on Males' and Females' Drug Use and Delinquency 9 Years After Baseline in a Community-Randomized Trial.American journal of community psychology · 2015Trial
- PROSPER partnership delivery system: Effects on adolescent conduct problem behavior outcomes through 6.5 years past baseline.Journal of adolescence · 2015Trial
- The conditioning of intervention effects on early adolescent alcohol use by maternal involvement and dopamine receptor D4 (DRD4) and serotonin transporter linked polymorphic region (5-HTTLPR) genetic variants.Development and psychopathology · 2015Trial
- A Within-Person Test of Mediated Pathways between Victimization, Internalizing Problems, and Antisocial Behavior in Early Adolescence.Journal of youth and adolescence · 2026Article
- The Role of Program Implementation Quality in Family-Focused Substance-Use Prevention for Youth with Multiple Risks: PROSPER Project.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Improvements in Capacity Among Community Coalitions Receiving Technical Assistance Through the Coalition Check-Up.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Friends Forever? Correlates of High School Friendship (In)stability from Adolescence to Young Adulthood.Social networks · 2025Article
- Community Coalition Functioning, Collaborative Structure, and Coalition Models: Enhancing Support for Evidence-Based Practice Implementation.Prevention science : the official journal of the Society for Prevention Research · 2025Article
- A case study in developmental discontinuity: PROSPER Interventions and adolescent substance use trajectories shape young adult substance use and mental health problems.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2024Article
- Tailoring opioid use prevention content for juvenile diversion programs with adolescents and their caregivers.Journal of substance use and addiction treatment · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
objectiveTo examine the effects of a delivery system for evidence-based preventive interventions through 12th grade, 6.5 years past baseline.
methodA cohort sequential design included 28 public school districts randomly assigned to the partnership delivery system or usual-programming conditions. At baseline, 11,960 students participated. Partnerships supported community teams that implemented a family-focused intervention in 6th grade and a school-based intervention in 7th grade. Outcome measures included lifetime, current misuse, and frequencies of misuse, for a range of substances. Intent-to-treat, multilevel analyses of covariance of point-in-time misuse and analyses of growth in misuse were conducted.
resultsResults showed significantly lower substance misuse in the intervention group at one or both time points for most outcomes, with relative reduction rates of up to 31.4%. There was significantly slower growth in misuse in the intervention group for 8 of the 10 outcomes. In addition, risk moderation results indicated that there were significantly greater intervention benefits for higher- versus lower-risk youth, for the misuse of 6 of the 10 substances at 11th grade, illicit substances at 12th grade, and growth in the misuse of illicit substances.
conclusionPartnership-based delivery systems for brief universal interventions have potential for public health impact by reducing substance misuse among youth, particularly higher-risk youth.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.