Trial reportPreventive medicine2013
Enhancing long-term weight loss maintenance: 2 year results from the Keep It Off randomized controlled trial.
Trial report in Preventive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 6 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- A systematic mapping review of individual participant factors related to eating disorder risk collected in behavioural weight management trials.Eating and weight disorders : EWD · 2026Pooled it
- Development of the Health Coaching Quality Index: A Proposed Method for Evaluating Health Coaching Interventions.International journal of behavioral medicine · 2026Pooled it
- A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Using health economic modelling to inform the design and development of an intervention: estimating the justifiable cost of weight loss maintenance in the UK.BMC public health · 2022Pooled it
- Pooled it
- Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials.BMJ (Clinical research ed.) · 2014Pooled it
- Change in Cardiometabolic Risk Factors Associated With Magnitude of Weight Regain 3 Years After a 1-Year Intensive Lifestyle Intervention in Type 2 Diabetes Mellitus: The Look AHEAD Trial.Journal of the American Heart Association · 2019Trial
- Behavioural intervention for weight loss maintenance versus standard weight advice in adults with obesity: A randomised controlled trial in the UK (NULevel Trial).PLoS medicine · 2019Trial
- Mediators of Weight Loss Maintenance in the Keep It Off Trial.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018Trial
- Maintenance of Weight Loss After Initiation of Nutrition Training: A Randomized Trial.Annals of internal medicine · 2017Trial
- Exploring Gender Differences in a Randomized Trial of Weight Loss Maintenance.American journal of men's health · 2017Trial
- Weight loss maintenance strategies among rural breast cancer survivors: The rural women connecting for better health trial.Obesity (Silver Spring, Md.) · 2016Trial
- Association between Self-Weighing and Percent Weight Change: Mediation Effects of Adherence to Energy Intake and Expenditure Goals.Journal of the Academy of Nutrition and Dietetics · 2016Trial
- Pediatric Primary Care-Based Obesity Prevention for Parents of Preschool Children: A Pilot Study.Childhood obesity (Print) · 2015Trial
- Trial
- Frequent Self-Weighing and Visual Feedback for Weight Loss in Overweight Adults.Journal of obesity · 2015Trial
- Weight loss maintenance for 2 years after a 6-month randomised controlled trial comparing education-only and group-based support in Japanese adults.Obesity facts · 2014Trial
- Binge eating behavior and weight loss maintenance over a 2-year period.Journal of obesity · 2014Trial
- Unpacking weight management interventions measuring eating disorder risk in adults: coding of components of interventions in a systematic review.Journal of eating disorders · 2026Review
- Design of Project STAR: A randomized controlled trial evaluating the impact of an adaptive intervention on long-term weight-loss maintenance.Contemporary clinical trials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe Keep It Off trial evaluated the efficacy of a phone-based weight loss maintenance intervention among adults who had recently lost weight in Minnesota (2007-2010).
methods419 adults who had recently lost ≥ 10% of their body weight were randomized to the "Guided" or "Self-Directed" intervention. Guided participants received a 10 session workbook, 10 biweekly, eight monthly and six bimonthly phone coaching calls, bimonthly weight graphs and tailored letters based on self-reported weights. Self-Directed participants received the workbook and two calls. Primary outcomes are weight change and maintenance (regain of <2.5% of baseline body weight).
resultsMixed model repeated-measures analysis examining weight change revealed a significant time by treatment group interaction (p<0.0085). Guided participants regained significantly less weight than the Self-Directed participants at 12 and 24 months. The odds of 24 month maintenance were 1.37 (95% CI: 0.97-2.03) times greater in the Guided than in the Self-Directed group. When maintenance rates were compared across all follow-ups, there was a consistently higher maintenance rate for Guided participants (HR 1.31, 95% CI: 1.12-1.54).
conclusionsA sustained, supportive phone- and mail-based intervention promotes weight loss maintenance relative to a brief intervention for participants who have recently lost weight.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.