Trial reportJournal of women's health (2002)2013
A comparison of Mediterranean-style and MyPyramid diets on weight loss and inflammatory biomarkers in postpartum breastfeeding women.
Trial report in Journal of women's health (2002), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lifestyle Intervention in Preparation for Pregnancy (LIPP)
Pregnancy, Active Duty and Weight Loss (PADaWL) Study: A Randomized Controlled Trial Assessing the Effect of Dietary Intervention on Postpartum Weight Loss in Active Duty Women
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The effects of consuming a Mediterranean style diet on associated COVID-19 severity biomarkers in obese/overweight adults: A systematic review.Nutrition and health · 2022Pooled it
- The Effect of the Traditional Mediterranean-Style Diet on Metabolic Risk Factors: A Meta-Analysis.Nutrients · 2016Pooled it
- Diet or exercise, or both, for weight reduction in women after childbirth.The Cochrane database of systematic reviews · 2013Pooled it
- Diet and exercise interventions among overweight and obese lactating women: randomized trial of effects on cardiovascular risk factors.PloS one · 2014Trial
- Mediterranean diet impact on plasma proteins: biomarker networks linking nutrition to the modulation of inflammation and oxidative stress.Frontiers in nutrition · 2026Review
- Mediterranean Diet Outcomes Across the Mother-Milk-Infant Triad: A Narrative Review.Nutrients · 2025Review
- Article
- Ten Recommendations for the Next Clinical Trial of the Mediterranean Diet in Inflamm-Aging: Results & Insights from a Scoping Review.JAR life · 2024Article
- A Mediterranean diet plan in lactating women with obesity reduces maternal energy intake and modulates human milk composition - a feasibility study.Frontiers in nutrition · 2024Article
- Which Diets Are Effective in Reducing Cardiovascular and Cancer Risk in Women with Obesity? An Integrative Review.Nutrients · 2021Review
- Rationale and study design for lifestyle intervention in preparation for pregnancy (LIPP): A randomized controlled trial.Contemporary clinical trials · 2020Article
- Supporting women of childbearing age in the prevention and treatment of overweight and obesity: a scoping review of randomized control trials of behavioral interventions.BMC women's health · 2020Article
- Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child.BMJ (Clinical research ed.) · 2017 · on this mapReview
- Adherence of pregnant women to Nordic dietary guidelines in relation to postpartum weight retention: results from the Norwegian Mother and Child Cohort Study.BMC public health · 2014Article
- Optimizing Weight for Maternal and Infant Health - Tenable, or Too Late?Expert review of endocrinology & metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOf postpartum women, 15%-20% retain ≥ 5 kg of their gestational weight gain, increasing risk for adult weight gain. Postpartum women are also in a persistent elevated inflammatory state. Both factors could increase the risk of obesity-related chronic disease. We hypothesized that breastfeeding women randomized to a Mediterranean-style (MED) diet for 4 months would demonstrate significantly greater reductions in body weight, body fat, and inflammation than women randomized to the U.S. Department of Agriculture's (USDA) MyPyramid diet for Pregnancy and Breastfeeding (comparison diet).
methodsA randomized, controlled dietary intervention trial was conducted in 129 overweight (body mass index [BMI] 27.2 ± 4.9 kg/m(2)), mostly exclusively breastfeeding (73.6%) women who were a mean 17.5 weeks postpartum. Dietary change was assessed using a validated Food Frequency Questionnaire (FFQ) before and after intervention as well as plasma fatty acid measures (gas chromatography/flame ionization detector [GC/FID]). Anthropometric measurements and biomarkers of inflammation, tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6), also were assessed at baseline and 4 months via enzyme-linked immunosorbent assay (ELISA).
resultsParticipants in both diet groups demonstrated significant (p<0.001) reductions in body weight (-2.3 ± 3.4 kg and -3.1 ± 3.4 kg for the MED and comparison diets, respectively) and significant (p ≤ 0.002) reductions in all other anthropometric measurements; no significant between-group differences were shown as hypothesized. A significant decrease in TNF-α but not IL-6 was also demonstrated in both diet groups, with no significant between-group difference.
conclusionsBoth diets support the promotion of postpartum weight loss and reduction in inflammation (TNF-α) in breastfeeding women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.