ArticleCase reports in dermatology2012
Pili annulati coincident with alopecia areata, autoimmune thyroid disease, and primary IgA deficiency: case report and considerations on the literature.
Article in Case reports in dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- An 8-year-old Girl with Multiple Whitish Dots on the Hair Shaft: A Quiz.Acta dermato-venereologica · 2026Article
- Pili Annulati in a Black-Haired Asian Woman.Clinical, cosmetic and investigational dermatology · 2026Article
- Ultraviolet Enhanced Trichoscopy - a New Tool to Assess Pili Annulati.Dermatology practical & conceptual · 2025Article
- Coexisting trichorrhexis nodosa and pili annulati: a case report of hair shaft abnormalities in a Syrian family.Annals of medicine and surgery (2012) · 2024Article
- Dermatologic manifestations of thyroid disease: a literature review.Frontiers in endocrinology · 2023Review
- Identification of Hair Growth Promoting Components in the Kernels ofMolecules (Basel, Switzerland) · 2022Article
- Genetic Hair Disorders: A Review.Dermatology and therapy · 2019Review
- Scanning Electron Microscopy of the Inner and Outer Aspects of Tiger Tail Hairs.International journal of trichologyArticle
- Hair Shaft Disorders in Children - An Update.Indian dermatology online journalReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pili annulati is a rare autosomal dominant hair disorder clinically characterized by a pattern of alternating bright and dark bands of the hair, the bright bands appearing dark if observed by transmitted light. This pattern is due to the periodic occurrence of air-filled cavities along the hair cortex which scatter and reflect the light while precluding its transmission. A susceptibility region, including a possibly responsible Frizzled gene, has been mapped to the telomeric region of chromosome 12q, although a specific mutation has not been identified. The condition has sometimes been observed in concurrence with alopecia areata, and in this paper we report a case in whom the concomitant severe alopecia areata was associated with autoimmune thyroid disease and primary IgA deficiency - a quadruple complex which, to our knowledge, has never been previously described. The occurrence of multiple immune disorders in the same patient affected by pili annulati could represent a key to understanding the high prevalence of alopecia areata in this condition. Specifically, in individuals predisposed to autoimmune disease, the molecular alterations that cause the anatomical changes of pili annulati could prompt the immune response against the hair root that underlies alopecia areata.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.