Evidence map›Paper›PMID 23275313›Full record

Trial reportBlood pressure monitoring2013

Linking clinic and home: a randomized, controlled clinical effectiveness trial of real-time, wireless blood pressure monitoring for older patients with kidney disease and hypertension.

Dena E Rifkin, Joseph A Abdelmalek, Cynthia M Miracle, Chai Low, Ryan Barsotti, Phil Rios, Carl Stepnowsky, Zia Agha

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Blood pressure monitoring, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06787599 (The Effect of Synchronous Homebased Tele-exercise on Physical Function, Daily Physical Activity and Frailty in Peritoneal Dialysis Patients), which is not on this map. Cited by 42 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06787599 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effect of Synchronous Homebased Tele-exercise on Physical Function, Daily Physical Activity and Frailty in Peritoneal Dialysis Patients: A Randomized Pilot Trial

TypeinterventionalSponsorPardis Specialized Wellness InstituteRan2025 to 2025Enrolled30ConditionsEnd Stage Renal Disease, Peritoneal Dialysis ComplicationArmsHome-based Tele Exercise
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Effect of pharmacist interventions in chronic kidney disease: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
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  11. eHealth interventions for people with chronic kidney disease.The Cochrane database of systematic reviews · 2019
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  15. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dena E RifkinDivision of Nephrology, University of California, San Diego, CA, USA. drifkin@ucsd.edu
Joseph A Abdelmalek
Cynthia M Miracle
Chai Low
Ryan Barsotti
Phil Rios
Carl Stepnowsky
Zia Agha

Funding

San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
SAN DIEGO CLINICAL AND TRANSLATIONAL RESEARCH INSTITUTEUL1RR031980 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2010 to 2011
$14.0M
Ambulatory BP, kidney function, cognitive & physical function in older adultsK23DK091521 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RIFKIN, DENA EVETTE · 2011 to 2015
$891k
Regulation of Kidney Oxygen ConsumptionK08DK078580 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MIRACLE, CYNTHIA MARIE · 2007 to 2011
$687k
NCATS NIH HHS UL1TR000100NCRR NIH HHS UL1 RR031980NCRR NIH HHS UL RR031980NIDDK NIH HHS K08 DK078580NIDDK NIH HHS K23 DK091521NIDDK NIH HHS K23DK091521-01
6 · The paper itself

Abstract

objectiveOlder adults with chronic kidney disease have a high rate of uncontrolled hypertension. Home monitoring of blood pressure (BP) is an integral part of management, but requires that patients bring records to clinic visits. Telemonitoring interventions, however, have not targeted older, less technologically-skilled populations.

methodsVeterans with stage 3 or greater chronic kidney disease and uncontrolled hypertension were randomized to a novel telemonitoring device pairing a Bluetooth-enabled BP cuff with an Internet-enabled hub, which wirelessly transmitted readings (n=28), or usual care (n=15). Home recordings were reviewed weekly and telemonitoring participants were contacted if BP was above goal. The prespecified primary endpoints were improved data exchange and device acceptability. Secondary endpoint was BP change.

resultsForty-three participants (average age 68 years, 75% white) completed the 6-month study. Average start-of-study BP was 147/78 mmHg. Those in the intervention arm had a median of 29 (IQR 22, 53) transmitted BP readings per month, with 78% continuing to use the device regularly, whereas only 20% of those in the usual care group brought readings to in-person visits. The median number of telephone contacts triggered by the wireless monitoring was 2 (IQR 1, 4) per patient. Both groups had a significant improvement in systolic BP (P<0.05, for both changes); systolic BP fell a median of 13 mmHg in monitored participants compared with 8.5 mmHg in usual care participants (P for comparison 0.31).

conclusionThis low-cost wireless monitoring strategy led to greater sharing of data between patients and clinic and produced a trend toward improvements in BP control over usual care at 6 months.

Indexed as

Blood Pressure Monitoring, AmbulatoryHypertensionInternetKidney DiseasesTelemedicineAdultAgedCosts and Cost AnalysisHumansMaleMiddle AgedTime Factors

Identifiers

PMID23275313
PMCPMC4111271

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.