ArticleThe Science of the total environment2013
Air pollution and respiratory symptoms among children with asthma: vulnerability by corticosteroid use and residence area.
Article in The Science of the total environment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- The Impact of Ambient Ozone Exposure on Respiratory Health in the U.S. Populations: A Systematic Review.Current environmental health reports · 2026Pooled it
- Asthma treatment response modified by fine particulate matter, nitrogen dioxide, and ozone among Black children: A reanalysis of the AsthmaNet Best African American Response to Asthma Drugs trial.The Journal of allergy and clinical immunology · 2025Trial
- Effects of short-term exposure to air pollution on respiratory symptoms and lung function among patients with asthma.Medical gas research · 2026Article
- Supplements and medications for respiratory resilience against air pollution.ERJ open research · 2026Review
- Genetic susceptibility to PMFrontiers in immunology · 2026Article
- Inequalities and indoor air pollution: a prospective observational study of particulate matter (PMBMC public health · 2025Observational
- Adrenergic receptor subtypes differentially influence acrolein-induced ventilatory, vascular leakage, and inflammatory responses.Toxicology and applied pharmacology · 2025Article
- Enhancer RNA transcription pinpoints functional genetic variants linked to asthma.Nature communications · 2025Article
- Article
- Ozone and childhood respiratory health: A primer for US pediatric providers and a call for a more protective standard.Pediatric pulmonology · 2023Review
- Urinary metabolites of polycyclic aromatic hydrocarbons and short-acting beta agonist or systemic corticosteroid asthma medication use within NHANES.Environmental research · 2023Article
- Race and Street-Level Firework Legalization as Primary Determinants of July 4th Air Pollution across Southern California.Atmosphere · 2023Article
- Respiratory health among adolescents living in the Highveld Air Pollution Priority Area in South Africa.BMC public health · 2022Article
- Article
- Exacerbation of ozone-induced pulmonary and systemic effects by βScientific reports · 2019Article
- Characterizing the joint effects of pesticide exposure and criteria ambient air pollutants on pediatric asthma morbidity in an agricultural community.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Acute respiratory symptoms associated with short term fluctuations in ambient pollutants among schoolchildren in Durban, South Africa.Environmental pollution (Barking, Essex : 1987) · 2018Article
- Environmental Health Priorities of Residents and Environmental Health Professionals: Implications for Improving Environmental Health Services in Rural Versus Urban Communities.Journal of environmental health · 2017Article
- Effects of Airborne Particulate Matter on Respiratory Health in a Community near a Cement Factory in Chilanga, Zambia: Results from a Panel Study.International journal of environmental research and public health · 2017Article
- Combustion-Related Organic Species in Temporally Resolved Urban Airborne Particulate Matter.Air quality, atmosphere, & health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
rationaleInformation on how ambient air pollution affects susceptible populations is needed to ensure protective air quality standards.
objectivesTo estimate the effect of community-level ambient particulate matter (PM) and ozone (O) on respiratory symptoms among primarily African-American and Latino, lower-income asthmatic children living in Detroit, Michigan and to evaluate factors associated with heterogeneity in observed health effects.
methodsA cohort of 298 children with asthma was studied prospectively from 1999 to 2002. For 14days each season over 11 seasons, children completed a respiratory symptom diary. Simultaneously, ambient pollutant concentrations were measured at two community-level monitoring sites. Logistic regression models using generalized estimating equations were fit for each respiratory symptom in single pollutant models, looking for interactions by area or by corticosteroid use, a marker of more severe asthma. Exposures of interest were: daily concentrations of PM<10μm, <2.5μm, and between 10 and 2.5μm in aerodynamic diameter (PM, PM, and PM respectively), the daily 8-hour maximum concentration of O (8HrPeak), and the daily 1-hour maximum concentration of O (1HrPeak).
resultsOutdoor PM, PM, 8HrPeak, and 1HrPeak O concentrations were associated with increased odds of respiratory symptoms, particularly among children using corticosteroid medication and among children living in the southwest community of Detroit. Similar patterns of associations were not seen with PM.
conclusionsPM and O at levels near or below annual standard levels are associated with negative health impact in this population of asthmatic children. Variation in effects within the city of Detroit and among the subgroup using steroids emphasizes the importance of spatially refined exposure assessment and the need for further studies to elucidate mechanisms and effective risk reduction interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.