ArticleOrganic letters2013
Total synthesis of kingianin A.
Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Cobalt catalyzed practical hydroboration of terminal alkynes with time-dependent stereoselectivity.Nature communications · 2024Article
- Stereoselective [2+2]-Cycloadditions of chiral allenic ketones and alkenes: Applications towards the synthesis of benzocyclobutenes and endiandric acids.Tetrahedron · 2022Article
- Bioinspired Asymmetric Total Synthesis of Emeriones A-C.Angewandte Chemie (International ed. in English) · 2022Article
- Total synthesis of endiandric acid J and beilcyclone A from cyclooctatetraene.Chemical science · 2020Article
- Bioinspired Synthesis of (-)-PF-1018.Angewandte Chemie (International ed. in English) · 2020Article
- Treasures old and new: what we can learn regarding the macrocyclic problem from past and present efforts in natural product total synthesis.RSC advances · 2020Review
- A Biomimetic Synthesis Elucidates the Origin of Preuisolactone A.Journal of the American Chemical Society · 2019Article
- The synthesis of some novel stilbene dimers incorporating diamide tethers: studies in single electron transfer oxidation (FeClRSC advances · 2018Article
- Characterizing Chain Processes in Visible Light Photoredox Catalysis.Chemical science · 2015Article
- Unified total synthesis of the natural products endiandric acid A, kingianic acid E, and kingianins A, D, and F.Chemical science · 2015Article
- Total synthesis of clostrubin.Nature communications · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A 12-step synthesis of kingianin A, an inhibitor of the antiapoptotic protein Bcl-xL, is based on a radical cation Diels-Alder reaction (RCDA). This approach is thought to be biomimetic. The use of a tether in the key RCDA step controls the regiochemistry of the cycloaddition, leading to the desired core structure and a separable diastereomer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.