ArticlePloS one2012
Prostatic stones: evidence of a specific chemistry related to infection and presence of bacterial imprints.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 71 citations in OpenAlex.
- A simplified algorithm for management of CP/CPPS and associated entities: A summary table for general urologists.Current urology · 2026Review
- Article
- Diagnosis and clinical significance of prostate calcification using computed tomography.Scientific reports · 2025Article
- Vulnerabilities of Prostate Glandular Concretions Considered as Artefacts: A Cross-sectional Biopsy Slide Study.Medeniyet medical journal · 2023Article
- Oxalate Homeostasis in Non-Stone-Forming Chronic Kidney Disease: A Review of Key Findings and Perspectives.Biomedicines · 2023Review
- The Microbiome and Urolithiasis: Current Advancements and Future Challenges.Current urology reports · 2022Review
- Pathological Mineralization: The Potential of Mineralomics.Materials (Basel, Switzerland) · 2019Review
- Predictors Of Postoperative Lower Urinary Tract Symptoms Improvements In Patient With Small-Volume Prostate And Bladder Outlet Obstruction.Therapeutics and clinical risk management · 2019Article
- Prostate calcifications: A case series supporting the microbial biofilm theory.Investigative and clinical urology · 2018Article
- Clinical Significance of Prostatic Calculi: A Review.The world journal of men's health · 2018Review
- Prospective Study on Association of Prostatic Calcifications with Clinical Symptoms and Results of Treatment in Men with type III prostatitis.Scientific reports · 2017Article
- Late Pleistocene/Early Holocene Evidence of Prostatic Stones at Al Khiday Cemetery, Central Sudan.PloS one · 2017Article
- Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained with Specific Antifungal Antibodies.Frontiers in neuroscience · 2016Article
- Relationships between pathology and crystal structure in breast calcifications: anNPJ breast cancer · 2016Article
- Prostate calculi can higher urinary retention probability and worsen uncomfortable feeling after prostate biopsy but not predict cancer.International journal of clinical and experimental medicine · 2015Article
- Infections and inflammation in prostate cancer.American journal of clinical and experimental urology · 2013Article
- Prostatic calculi in men with chronic prostatitis and chronic pelvic pain syndrome: A systematic review (2015-2025).Urology annalsReview
- The burden of prostatic calculi is more important than the presence.Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prostatic stones are a common condition in older men in industrialized countries. However, aging appears not to be the unique pathogenesis of these calcifications. Our morpho-constitutional investigation of 23 stone samples suggested that infection has a significant role in the lithogenic process of prostate calcifications, even without detection of infection by clinical investigation. Most stones (83%) showed bacterial imprints and/or chemical composition, suggestive of a long-term infection process. Chronic infection may induce persistent inflammation of the tissue and secondarily, a cancerization process within a few years. Thus, the discovery of prostate calcifications by computerized tomodensitometry, for example, might warrant further investigation and management to search for chronic infection of the prostate gland.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.