Evidence map›Paper›PMID 23271646›Full record

ReviewJournal of cardiovascular translational research2013

Clinical implications of platelet-vessel interaction.

Fabio Mangiacapra, Emanuele Barbato

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. The role of platelets in sepsis: A review.Biomolecules & biomedicine · 2024
    Review
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fabio MangiacapraCardiovascular Center Aalst, OLV Clinic, Moorselbaan 164, 9300 Aalst, Belgium.
Emanuele Barbato
Onze Lieve Vrouwziekenhuis Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction of platelets with endothelial and inflammatory cells might trigger atherogenesis. Different pathways are responsible for this contribution of platelets to atherogenesis. A significant association has been described between increased platelet activation and the extent of atherosclerosis. Platelet reactivity also plays a key role in determining outcomes of patients undergoing percutaneous coronary intervention (PCI). Despite dual antiplatelet therapy, platelet reactivity increases early after the procedure proportionally to the degree of vascular damage and endothelial dysfunction induced by coronary interventions, and large increases in platelet reactivity are also associated with an increased risk of periprocedural myonecrosis. The interaction between platelets and vessel wall has important clinical implications, especially in patients treated with PCI. These include the appropriate selection of antiplatelet drugs when more aggressive procedures are needed, the prognostic significance of periprocedural variations of platelet reactivity, and the correct timing for platelet function testing.

Indexed as

Platelet ActivationAnimalsAtherosclerosisBlood PlateletsBlood VesselsEndothelial CellsHumansPercutaneous Coronary InterventionPlatelet AdhesivenessPlatelet Aggregation InhibitorsPlatelet Function TestsThrombosisPlatelet Aggregation Inhibitors

Identifiers

PMID23271646
OpenAlexW1999920390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.